Brendan A Hilliard
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Explore the profile of Brendan A Hilliard including associated specialties, affiliations and a list of published articles.
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19
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617
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Recent Articles
1.
Patel P, Tamas I, Van Der Bas M, Kegg A, Hilliard B, Lambi A, et al.
Int J Mol Sci
. 2025 Jan;
25(24).
PMID: 39769311
Overuse injury is a frequent diagnosis in occupational medicine and athletics. Using an established model of upper extremity overuse, we sought to characterize changes occurring in the forepaws and forelimbs...
2.
Barbe M, Chen F, Loomis R, Harris M, Kim B, Xie K, et al.
Front Pain Res (Lausanne)
. 2024 May;
5:1394017.
PMID: 38770243
Introduction: Low back pain is the most common type of chronic pain. We examined pain-related behaviors across 18 weeks in rats that received injury to one or two lumbar intervertebral...
3.
Tiwari E, Porreca D, Braverman A, Holt-Bright L, Frara N, Brown J, et al.
Am J Physiol Regul Integr Comp Physiol
. 2024 Mar;
326(6):R528-R551.
PMID: 38497126
In pilot work, we showed that somatic nerve transfers can restore motor function in long-term decentralized dogs. We continue to explore the effectiveness of motor reinnervation in 30 female dogs....
4.
Hilliard B, Amin M, Popoff S, Barbe M
Int J Mol Sci
. 2024 Feb;
25(3).
PMID: 38339140
A role for substance P has been proposed in musculoskeletal fibrosis, with effects mediated through transforming growth factor beta (TGFβ). We examined the in vitro effects of substance P on...
5.
Klyne D, Hilliard B, Harris M, Amin M, Hall M, Besomi M, et al.
Brain Behav Immun Health
. 2023 Dec;
35:100714.
PMID: 38111687
Poor sleep is thought to enhance pain via increasing peripheral and/or central sensitization. Aerobic exercise, conversely, relives pain via reducing sensitization, among other mechanisms. This raises two clinical questions: (1)...
6.
Lambi A, DeSante R, Patel P, Hilliard B, Popoff S, Barbe M
Int J Mol Sci
. 2023 Sep;
24(18).
PMID: 37762168
The matricellular protein cell communication factor 2/connective tissue growth factor (CCN2/CTGF) is critical to development of neuromuscular fibrosis. Here, we tested whether anti-CCN2 antibody treatment will reduce established forepaw fibro-degenerative...
7.
Lambi A, Harris M, Amin M, Joiner P, Hilliard B, Assari S, et al.
JBMR Plus
. 2023 Sep;
7(9):e10783.
PMID: 37701153
We have an operant model of reaching and grasping in which detrimental bone remodeling is observed rather than beneficial adaptation when rats perform a high-repetition, high-force (HRHF) task long term....
8.
Hilliard B, Amin M, Popoff S, Barbe M
Connect Tissue Res
. 2020 Oct;
62(1):133-149.
PMID: 33030055
Aim: To examine the chronic effect of force on mRNA and protein expression levels of fibrosis-related genes in flexor digitorum muscles in a rat model of repetitive overuse injury that...
9.
Barbe M, Hilliard B, Amin M, Harris M, Hobson L, Cruz G, et al.
J Orthop Res
. 2020 May;
38(11):2396-2408.
PMID: 32379362
Encapsulation of median nerves is a hallmark of overuse-induced median mononeuropathy and contributes to functional declines. We tested if an antibody against CTGF/CCN2 (termed FG-3019 or Pamrevlumab) reduces established neural...
10.
Barbe M, Hilliard B, Amin M, Harris M, Hobson L, Cruz G, et al.
FASEB J
. 2020 Apr;
34(5):6554-6569.
PMID: 32227398
Tissue fibrosis is a hallmark of overuse musculoskeletal injuries and contributes to functional declines. We tested whether inhibition of CCN2 (cellular communication network factor 2, previously known as connective tissue...