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Brendan A C Harley

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Articles 117
Citations 2064
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Recent Articles
21.
Cosgriff-Hernandez E, Aguado B, Akpa B, Fleming G, Moore E, Porras A, et al.
Nat Biomed Eng . 2023 Aug; 7(8):961-968. PMID: 37580521
No abstract available.
22.
Ren X, Zhou Q, Bedar M, Foulad D, Huang K, Dejam D, et al.
Adv Healthc Mater . 2023 Mar; 12(17):e2202750. PMID: 36863404
The temporospatial equilibrium of phosphate contributes to physiological bone development and fracture healing, yet optimal control of phosphate content has not been explored in skeletal regenerative materials. Nanoparticulate mineralized collagen...
23.
Dewey M, Collins A, Tiffany A, Barnhouse V, Lu C, Kolliopoulos V, et al.
Biomaterials . 2023 Jan; 294:122015. PMID: 36701999
The design of biomaterials to regenerate bone is likely to increasingly require modifications that reduce bacterial attachment and biofilm formation as infection during wound regeneration can significantly impede tissue repair...
24.
Ren X, Dejam D, Oberoi M, Dahan N, Zhou Q, Huang K, et al.
Biomater Adv . 2022 Dec; 145:213262. PMID: 36565669
Custom synthesis of extracellular matrix (ECM)-inspired materials for condition-specific reconstruction has emerged as a potentially translatable regenerative strategy. In skull defect reconstruction, nanoparticulate mineralized collagen glycosaminoglycan scaffolds (MC-GAG) have demonstrated...
25.
Kolliopoulos V, Dewey M, Polanek M, Xu H, Harley B
Front Bioeng Biotechnol . 2022 Dec; 10:1034701. PMID: 36466348
Craniomaxillofacial (CMF) bone injuries present a major surgical challenge and cannot heal naturally due to their large size and complex topography. We are developing a mineralized collagen scaffold that mimics...
26.
Ngo M, Sarkaria J, Harley B
Adv Sci (Weinh) . 2022 Sep; 9(31):e2201888. PMID: 36109186
Glioblastoma (GBM) tumor cells are found in the perivascular niche microenvironment and are believed to associate closely with the brain microvasculature. However, it is largely unknown how the resident cells...
27.
Pastrana-Otero I, Majumdar S, Gilchrist A, Harley B, Kraft M
Anal Chem . 2022 Aug; 94(35):11999-12007. PMID: 36001072
Efforts to expand hematopoietic stem and progenitor cells (HSPCs) in vitro are motivated by their use in the treatment of leukemias and other blood and immune system diseases. The combinations...
28.
Zambuto S, Jain I, Clancy K, Underhill G, Harley B
ACS Biomater Sci Eng . 2022 Aug; 8(9):3819-3830. PMID: 35994527
The endometrium undergoes profound changes in tissue architecture and composition, both during the menstrual cycle as well as in the context of pregnancy. Dynamic remodeling processes of the endometrial extracellular...
29.
Tiffany A, Harley B
Adv Healthc Mater . 2022 Jul; 11(19):e2200471. PMID: 35905390
Growth plates, or physis, are highly specialized cartilage tissues responsible for longitudinal bone growth in children and adolescents. Chondrocytes that reside in growth plates are organized into three distinct zones...
30.
Ngo M, Barnhouse V, Gilchrist A, Mahadik B, Hunter C, Hensold J, et al.
Adv Funct Mater . 2022 May; 31(51). PMID: 35558090
Biomaterials that replicate patterns of microenvironmental signals from the stem cell niche offer the potential to refine platforms to regulate stem cell behavior. While significant emphasis has been placed on...