Brendan A C Harley
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Explore the profile of Brendan A C Harley including associated specialties, affiliations and a list of published articles.
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117
Citations
2064
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Recent Articles
11.
Thompson G, Gilchrist A, Lam V, Nunes A, Payan B, Mora-Boza A, et al.
J Biomed Mater Res A
. 2024 Jun;
112(12):2124-2135.
PMID: 38894666
Hematopoietic stem cells (HSCs) are the apical cells of the hematopoietic system, giving rise to cells of the blood and lymph lineages. HSCs reside primarily within bone marrow niches that...
12.
Chen W, Bedar M, Zhou Q, Ren X, Kang Y, Huang K, et al.
Adv Healthc Mater
. 2024 Jun;
13(26):e2401037.
PMID: 38885525
Precision material design directed by cell biological processes represents a frontier in developing clinically translatable regenerative technologies. While understanding cell-material interactions on multipotent progenitor cells yields insights on target tissue...
13.
Zambuto S, Jain I, Theriault H, Underhill G, Harley B
Adv Healthc Mater
. 2024 Jan;
13(12):e2303928.
PMID: 38291861
Chirality is an intrinsic cellular property that describes cell polarization biases along the left-right axis, apicobasal axis, or front-rear axes. Cell chirality plays a significant role in the arrangement of...
14.
Kriuchkovskaia V, Eames E, Riggins R, Harley B
bioRxiv
. 2023 Nov;
PMID: 38014332
Teaser: A hydrogel model to investigate the impact of acquired drug resistance on functional response in glioblastoma.
15.
Kolliopoulos V, Tiffany A, Polanek M, Harley B
bioRxiv
. 2023 Nov;
PMID: 38014316
Contemporary tissue engineering efforts often seek to use mesenchymal stem cells (MSCs) due to their potential to differentiate to various tissue-specific cells and generate a pro-regenerative secretome. While MSC differentiation...
16.
Zambuto S, Jain I, Theriault H, Underhill G, Harley B
bioRxiv
. 2023 Nov;
PMID: 37961315
Chirality is an intrinsic cellular property that describes cell polarization biases along the left-right axis, apicobasal axis, or front-rear axes. Cell chirality plays a significant role in the arrangement of...
17.
Dewey M, Timmer K, Blystone A, Lu C, Harley B
J Biomed Mater Res A
. 2023 Oct;
112(3):336-347.
PMID: 37861296
Current treatments for craniomaxillofacial (CMF) defects motivate the design of instructive biomaterials that can promote osteogenic healing of complex bone defects. We report methods to promote in vitro osteogenesis of...
18.
Dewey M, Chang R, Nosatov A, Janssen K, Crotts S, Hollister S, et al.
Acta Biomater
. 2023 Oct;
172:249-259.
PMID: 37806375
Regenerative biomaterials for musculoskeletal defects must address multi-scale mechanical challenges. Repairing craniomaxillofacial bone defects, which are often large and irregularly shaped, requires close conformal contact between implant and defect margins...
19.
Dewey M, Chang R, Nosatov A, Janssen K, Crotts S, Hollister S, et al.
bioRxiv
. 2023 Sep;
PMID: 37732275
Regenerative biomaterials for musculoskeletal defects must address multi-scale mechanical challenges. We are developing biomaterials for craniomaxillofacial bone defects that are often large and irregularly shaped. These require close conformal contact...
20.
Lumibao J, Haak P, Kolossov V, Chen J, Stutchman J, Ruiz A, et al.
Int J Oncol
. 2023 Sep;
63(5).
PMID: 37654190
Glioblastoma (GBM) is the most common and malignant primary brain tumor affecting adults and remains incurable. The mitochondrial coiled‑coil‑helix‑coiled‑coil‑helix domain‑containing protein 2 (CHCHD2) has been demonstrated to mediate mitochondrial respiration,...