Brendan A C Harley
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Explore the profile of Brendan A C Harley including associated specialties, affiliations and a list of published articles.
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117
Citations
2064
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Recent Articles
1.
Theriault H, Kimmel H, Nunes A, Paxhia A, Hashim S, Clancy K, et al.
bioRxiv
. 2025 Mar;
PMID: 40060608
Due to the extended period for clinical diagnosis, the etiology of endometriotic lesion initiation is not well understood or characterized. Endometriotic lesions are most often found on pelvic tissues and...
2.
Thompson G, Barnhouse V, Bierman S, Harley B
bioRxiv
. 2025 Mar;
PMID: 40060591
Hematopoietic stem cell (HSC) fate is shaped by distinct microenvironments termed niches within the bone marrow. Quiescence, expansion, and differentiation are directly and indirectly regulated by complex combinations of cell...
3.
Chang C, Bale A, Bhargava R, Harley B
Mater Today Bio
. 2025 Feb;
31:101475.
PMID: 39896278
Glioblastoma (GBM) is the most common and lethal form of primary brain cancer. Microglia infiltration into the tumor microenvironment is associated with immunosuppression and poor prognosis. Improved physicochemical understanding of...
4.
Chang C, Bale A, Bhargava R, Harley B
bioRxiv
. 2024 Nov;
PMID: 39605524
Glioblastoma (GBM) is the most common and lethal form of primary brain cancer. Microglia infiltration into the tumor microenvironment is associated with immunosuppression and poor prognosis. Improved physicochemical understanding of...
5.
Adorno G, Timmer K, Chang R, Shi J, Rogers S, Harley B
bioRxiv
. 2024 Oct;
PMID: 39464090
Injuries to musculoskeletal interfaces, such as the tendon-to-bone insertion of the rotator cuff, present significant physiological and clinical challenges for repair due to complex gradients of structure, composition, and cellularity....
6.
Zambuto S, Kolluru S, Harley B, Oyen M
Placenta
. 2024 Sep;
157:67-75.
PMID: 39341721
Rising maternal mortality rates in the U.S. are a significant public health issue that must be addressed; however, much of the basic science information required to target pregnancy-related pathologies have...
7.
Timmer K, Killian M, Harley B
Biomater Sci
. 2024 Aug;
12(18):4806-4822.
PMID: 39150417
Rotator cuff injuries present a clinical challenge for repair due to current limitations in functional regeneration of the native tendon-to-bone enthesis. A biomaterial that can regionally instruct unique tissue-specific phenotypes...
8.
Donor Sex and Passage Conditions Influence MSC Osteogenic Response in Mineralized Collagen Scaffolds
Kolliopoulos V, Tiffany A, Polanek M, Harley B
Adv Healthc Mater
. 2024 Jul;
13(27):e2400039.
PMID: 39036820
Contemporary tissue engineering efforts often seek to use mesenchymal stem cells (MSCs) due to their multi-potent potential and ability to generate a pro-regenerative secretome. While many have reported the influence...
9.
Zambuto S, Theriault H, Jain I, Crosby C, Pintescu I, Chiou N, et al.
NPJ Womens Health
. 2024 Jul;
2(1).
PMID: 39036057
The endometrium undergoes rapid cycles of vascular growth, remodeling, and breakdown during the menstrual cycle and pregnancy. Decidualization is an endometrial differentiation process driven by steroidal sex hormones that is...
10.
Kriuchkovskaia V, Eames E, Riggins R, Harley B
Adv Healthc Mater
. 2024 Jul;
13(27):e2400779.
PMID: 39030879
Acquired drug resistance in glioblastoma (GBM) presents a major clinical challenge and is a key factor contributing to abysmal prognosis, with less than 15 months median overall survival. Aggressive chemotherapy...