BreAnne Poirier
Overview
Explore the profile of BreAnne Poirier including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
237
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0
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Recent Articles
1.
Reilly S, Abu-Odeh M, Ameka M, DeLuca J, Naber M, Dadpey B, et al.
J Clin Invest
. 2021 Apr;
131(10).
PMID: 33822771
The protein kinases IKKε and TBK1 are activated in liver and fat in mouse models of obesity. We have previously demonstrated that treatment with the IKKε/TBK1 inhibitor amlexanox produces weight...
2.
Reilly S, Hung C, Ahmadian M, Zhao P, Keinan O, Gomez A, et al.
Nat Metab
. 2020 Jul;
2(7):620-634.
PMID: 32694788
Catecholamines stimulate the mobilization of stored triglycerides in adipocytes to provide fatty acids (FAs) for other tissues. However, a large proportion is taken back up and either oxidized or re-esterified....
3.
Gomez-Banoy N, Guseh J, Li G, Rubio-Navarro A, Chen T, Poirier B, et al.
Nat Med
. 2019 Nov;
25(11):1739-1747.
PMID: 31700183
Type 2 diabetes is characterized by insulin resistance and a gradual loss of pancreatic beta cell mass and function. Currently, there are no therapies proven to prevent beta cell loss...
4.
Oral E, Reilly S, Gomez A, Meral R, Butz L, Ajluni N, et al.
Cell Metab
. 2017 Jul;
26(1):157-170.e7.
PMID: 28683283
Numerous studies indicate an inflammatory link between obesity and type 2 diabetes. The inflammatory kinases IKKɛ and TBK1 are elevated in obesity; their inhibition in obese mice reduces weight, insulin...
5.
Reilly S, Ahmadian M, Zamarron B, Chang L, Uhm M, Poirier B, et al.
Nat Commun
. 2015 Jan;
6:6047.
PMID: 25581158
The search for effective treatments for obesity and its comorbidities is of prime importance. We previously identified IKK-ε and TBK1 as promising therapeutic targets for the treatment of obesity and...