Brandon Wainwright
Overview
Explore the profile of Brandon Wainwright including associated specialties, affiliations and a list of published articles.
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Articles
22
Citations
1081
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0
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Recent Articles
1.
Li Y, Lim C, Dismuke T, Malawsky D, Oasa S, Bruce Z, et al.
Nat Commun
. 2025 Feb;
16(1):1091.
PMID: 39904981
OLIG2-expressing tumor stem cells have been shown to drive recurrence in Sonic Hedgehog (SHH)-subgroup medulloblastoma (MB) and patients urgently need specific therapies to target this tumor cell population. Here, we...
2.
Hansford J, Valvi S, de Boer J, McCowage G, Govender D, Kirby M, et al.
Med J Aust
. 2024 Nov;
221(10):520-523.
PMID: 39508471
No abstract available.
3.
Li Y, Lim C, Dismuke T, Malawsky D, Oasa S, Bruce Z, et al.
Res Sq
. 2023 Jun;
PMID: 37333134
Recurrence is the primary life-threatening complication for medulloblastoma (MB). In Sonic Hedgehog (SHH)-subgroup MB, OLIG2-expressing tumor stem cells drive recurrence. We investigated the anti-tumor potential of the small-molecule OLIG2 inhibitor...
4.
Villani R, Sim S, Roy E, Wainwright B, Francois M, Khosrotehrani K
J Dermatol Sci
. 2020 May;
98(3):179-185.
PMID: 32444239
Background: Basal Cell Carcinoma is the most common tumour and yet much remains to be determined regarding the molecular mechanisms that leads to its development. Hedgehog signal activation is sufficient...
5.
Robson J, Remke M, Kool M, Julian E, Korshunov A, Pfister S, et al.
PLoS One
. 2019 Jan;
14(1):e0210665.
PMID: 30657775
High morbidity and mortality are common traits of malignant tumours and identification of the cells responsible is a focus of on-going research. Many studies are now reporting the use of...
6.
Kojic M, Wainwright B
Front Mol Neurosci
. 2016 Nov;
9:115.
PMID: 27847465
Development of the nervous system requires a variety of cellular activities, such as proliferation, migration, axonal outgrowth and guidance and synapse formation during the differentiation of neural precursors into mature...
7.
Adolphe C, Junker J, Lyubimova A, van Oudenaarden A, Wainwright B
J Invest Dermatol
. 2016 Aug;
137(1):179-186.
PMID: 27498049
By using the sensitivity of single-molecule fluorescent in situ hybridization, we have precisely quantified the levels and defined the temporal and spatial distribution of Hedgehog signaling activity during embryonic skin...
8.
Palmer C, Galan-Caridad J, Weisberg S, Lei L, Esquilin J, Croft G, et al.
Cancer Res
. 2014 Aug;
74(20):5914-24.
PMID: 25164012
The Hedgehog (Hh) signaling pathway regulates normal development and cell proliferation in metazoan organisms, but its aberrant activation can promote tumorigenesis. Hh-induced tumors arise from various tissues and they may...
9.
Gottardo N, Hansford J, McGlade J, Alvaro F, Ashley D, Bailey S, et al.
Acta Neuropathol
. 2013 Nov;
127(2):189-201.
PMID: 24264598
Medulloblastoma is curable in approximately 70% of patients. Over the past decade, progress in improving survival using conventional therapies has stalled, resulting in reduced quality of life due to treatment-related...
10.
Fan Q, Gu D, He M, Liu H, Sheng T, Xie G, et al.
Chin J Cancer
. 2011 Jul;
30(7):472-81.
PMID: 21718593
The link of hedgehog (Hh) signaling activation to human cancer and synthesis of a variety of Hh signaling inhibitors raise great expectation that inhibiting Hh signaling may be effective in...