Brandon T Pfannenstiel
Overview
Explore the profile of Brandon T Pfannenstiel including associated specialties, affiliations and a list of published articles.
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10
Citations
218
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Recent Articles
1.
Karahoda B, Pfannenstiel B, Sarikaya-Bayram O, Dong Z, Wong K, Fleming A, et al.
Fungal Genet Biol
. 2023 Sep;
169:103836.
PMID: 37666447
The filamentous fungus Aspergillus flavus is a plant and human pathogen predominantly found in the soil as spores or sclerotia and is capable of producing various secondary metabolites (SM) such...
2.
Karahoda B, Pardeshi L, Ulas M, Dong Z, Shirgaonkar N, Guo S, et al.
Nucleic Acids Res
. 2022 Sep;
50(17):9797-9813.
PMID: 36095118
Chromatin complexes control a vast number of epigenetic developmental processes. Filamentous fungi present an important clade of microbes with poor understanding of underlying epigenetic mechanisms. Here, we describe a chromatin...
3.
Drott M, Satterlee T, Skerker J, Pfannenstiel B, Glass N, Keller N, et al.
mBio
. 2020 Jul;
11(4).
PMID: 32665272
The apparent rarity of sex in many fungal species has raised questions about how much sex is needed to purge deleterious mutations and how differences in frequency of sex impact...
4.
Baccile J, Le H, Pfannenstiel B, Bok J, Gomez C, Brandenburger E, et al.
Angew Chem Int Ed Engl
. 2019 Jul;
58(41):14589-14593.
PMID: 31342608
Cyclization of linear dipeptidyl precursors derived from nonribosomal peptide synthetases (NRPSs) into 2,5-diketopiperazines (DKPs) is a crucial step in the biosynthesis of a large number of bioactive natural products. However,...
5.
Greco C, Pfannenstiel B, Liu J, Keller N
ACS Chem Biol
. 2019 May;
14(6):1121-1128.
PMID: 31117395
Expression of biosynthetic gene clusters (BGCs) in filamentous fungi is highly regulated by epigenetic remodeling of chromatin structure. Two classes of histone modifying proteins, writers (which place modifications on histone...
6.
Pfannenstiel B, Keller N
Biotechnol Adv
. 2019 Feb;
37(6):107345.
PMID: 30738111
Fungi produce an abundance of bioactive secondary metabolites which can be utilized as antibiotics and pharmaceutical drugs. The genes encoding secondary metabolites are contiguously arranged in biosynthetic gene clusters (BGCs),...
7.
Pfannenstiel B, Greco C, Sukowaty A, Keller N
Fungal Genet Biol
. 2018 Aug;
120:9-18.
PMID: 30130575
Due to the role, both beneficial and harmful, that fungal secondary metabolites play in society, the study of their regulation is of great importance. Genes for any one secondary metabolite...
8.
Pfannenstiel B, Zhao X, Wortman J, Wiemann P, Throckmorton K, Spraker J, et al.
mBio
. 2017 Sep;
8(5).
PMID: 28874473
The study of aflatoxin in spp. has garnered the attention of many researchers due to aflatoxin's carcinogenic properties and frequency as a food and feed contaminant. Significant progress has been...
9.
Alexander W, Peris D, Pfannenstiel B, Opulente D, Kuang M, Hittinger C
Fungal Genet Biol
. 2015 Nov;
89:10-17.
PMID: 26555931
Saccharomyces interspecies hybrids are critical biocatalysts in the fermented beverage industry, including in the production of lager beers, Belgian ales, ciders, and cold-fermented wines. Current methods for making synthetic interspecies...
10.
Downes D, Chonofsky M, Tan K, Pfannenstiel B, Reck-Peterson S, Todd R
G3 (Bethesda)
. 2014 Oct;
4(12):2483-92.
PMID: 25352541
4-Nitroquinoline 1-oxide (4-NQO) is a highly carcinogenic chemical that induces mutations in bacteria, fungi, and animals through the formation of bulky purine adducts. 4-NQO has been used as a mutagen...