Brandon M Murphy
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Explore the profile of Brandon M Murphy including associated specialties, affiliations and a list of published articles.
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9
Citations
69
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Recent Articles
1.
Gillis K, Orellana W, Wilson E, Parnell T, Fort G, Fang P, et al.
Dev Cell
. 2024 Nov;
60(3):472-489.e8.
PMID: 39515329
The ability of cancer cells to undergo identity changes (i.e., lineage plasticity) plays a key role in tumor progression and response to therapy. Loss of the pulmonary lineage specifier NKX2-1...
2.
Murphy B, Jensen D, Arnold T, Aguilar-Valenzuela R, Hughes J, Posada V, et al.
Pigment Cell Melanoma Res
. 2023 Jun;
36(5):365-377.
PMID: 37341054
An increasing number of cancer subtypes are treated with front-line immunotherapy. However, approaches to overcome primary and acquired resistance remain limited. Preclinical mouse models are often used to investigate resistance...
3.
Weiss T, Crawford E, Posada V, Rahman H, Liu T, Murphy B, et al.
Pigment Cell Melanoma Res
. 2022 Sep;
36(1):6-18.
PMID: 36148789
Melanin is a free-radical scavenger, antioxidant, and broadband absorber of ultraviolet (UV) radiation which protects the skin from environmental carcinogenesis. However, melanin synthesis and UV-induced reactive melanin species are also...
4.
Murphy B, Burd C
Cancer Cell
. 2022 Jul;
40(8):815-817.
PMID: 35868308
In a recent publication in Nature, Fane et al. establish WNT5A as a central, age-sensitive regulator of the dormancy-to-reactivation axis of melanoma. They show that aged fibroblasts in the lungs...
5.
Murphy B, Terrell E, Chirasani V, Weiss T, Lew R, Holderbaum A, et al.
Nat Commun
. 2022 Jun;
13(1):3153.
PMID: 35672316
A distinct profile of NRAS mutants is observed in each tumor type. It is unclear whether these profiles are determined by mutagenic events or functional differences between NRAS oncoproteins. Here,...
6.
Bowman R, Hennessey R, Weiss T, Tallman D, Crawford E, Murphy B, et al.
Life Sci Alliance
. 2021 Jul;
4(9).
PMID: 34210801
-mutant melanomas are more likely than -mutant melanomas to arise in anatomical locations protected from chronic sun damage. We hypothesized that this discrepancy in tumor location is a consequence of...
7.
Murphy B, Burd C
J Invest Dermatol
. 2019 Aug;
139(9):1857-1859.
PMID: 31445573
The clinical management of large and giant congenital melanocytic nevi (lgCMN) relies heavily upon iterative surgical procedures. In this issue Rouille et al. (2019) use lgCMN explants and a newly...
8.
Murphy B, Weiss T, Burd C
J Vis Exp
. 2019 Jul;
(148).
PMID: 31305511
Defects in fibroblast or melanocyte function are associated with skin diseases, including poor barrier function, defective wound healing, pigmentation defects and cancer. Vital to the understanding and amelioration of these...
9.
Panfil A, Dissinger N, Howard C, Murphy B, Landes K, Fernandez S, et al.
J Virol
. 2016 Jan;
90(7):3760-72.
PMID: 26819304
Unlabelled: Human T-cell leukemia virus type 1 (HTLV-1) and type 2 (HTLV-2) are highly related retroviruses that transform T cells in vitro but have distinct pathological outcomes in vivo. HTLV-1...