Brandon M Huffman
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Explore the profile of Brandon M Huffman including associated specialties, affiliations and a list of published articles.
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30
Citations
202
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Recent Articles
1.
Lander E, Aushev V, Huffman B, Hanna D, Dutta P, Ferguson J, et al.
JCO Precis Oncol
. 2024 Dec;
8:e2400288.
PMID: 39642325
Purpose: After neoadjuvant therapy (NAT) and surgery, up to one third and one half of patients with esophagogastric adenocarcinoma with a pathologic complete response (pCR; tumor regression grade 0 [TRG-0])...
2.
Huffman B, Rahma O, Tyan K, Li Y, Giobbie-Hurder A, Schlechter B, et al.
Cancer Immunol Res
. 2024 Sep;
13(1):9-22.
PMID: 39348472
Ovarian cancers and microsatellite stable (MSS) colorectal cancers are insensitive to anti-programmed cell death 1 (PD-1) immunotherapy, and new immunotherapeutic approaches are needed. Preclinical data suggest a relationship between immunotherapy...
3.
Singh H, Xiu J, Kapner K, Yuan C, Narayan R, Oberley M, et al.
Clin Cancer Res
. 2024 Sep;
30(21):4932-4942.
PMID: 39283131
Purpose: Transcriptional profiling of pancreatic cancers has defined two main transcriptional subtypes: classical and basal. Initial data suggest shorter survival for patients with basal tumors and differing treatment sensitivity to...
4.
Oberstein P, Dias Costa A, Kawaler E, Cardot-Ruffino V, Rahma O, Beri N, et al.
Cancer Immunol Res
. 2024 Jul;
12(9):1221-1235.
PMID: 38990554
Innate inflammation promotes tumor development, although the role of innate inflammatory cytokines in established human tumors is unclear. Herein, we report clinical and translational results from a phase Ib trial...
5.
Jayakrishnan T, Yadav D, Huffman B, Cleary J
Curr Oncol Rep
. 2024 Jun;
26(8):967-976.
PMID: 38861124
Purpose Of Review: Squamous cell carcinoma of the anus (SCCA) is an HPV-associated malignancy that has limited treatment options. Immunotherapy has expanded these options and here we review current and...
6.
Bauer A, Alkhateeb K, Agoston A, Odze R, Joshi M, Huffman B, et al.
Am J Surg Pathol
. 2024 May;
48(7):883-889.
PMID: 38726899
The role of Human papillomavirus (HPV) infection in esophageal squamous cell carcinoma (ESCC) is a topic of ongoing debate. This study used two screening approaches to look for evidence of...
7.
Prosz A, Sahgal P, Huffman B, Sztupinszki Z, Morris C, Chen D, et al.
NPJ Precis Oncol
. 2024 May;
8(1):98.
PMID: 38710943
No abstract available.
8.
Prosz A, Sahgal P, Huffman B, Sztupinszki Z, Morris C, Chen D, et al.
NPJ Precis Oncol
. 2024 Apr;
8(1):87.
PMID: 38589664
Homologous recombination (HR) and nucleotide excision repair (NER) are the two most frequently disabled DNA repair pathways in cancer. HR-deficient breast, ovarian, pancreatic and prostate cancers respond well to platinum...
9.
Singh H, Sahgal P, Kapner K, Corsello S, Gupta H, Gujrathi R, et al.
Clin Cancer Res
. 2024 Feb;
30(8):1669-1684.
PMID: 38345769
Purpose: ERBB2-amplified colorectal cancer is a distinct molecular subtype with expanding treatments. Implications of concurrent oncogenic RAS/RAF alterations are not known. Experimental Design: Dana-Farber and Foundation Medicine Inc. Colorectal cancer...
10.
Huffman B, Singh H, Ali L, Horick N, Wang S, Hoffman M, et al.
J Immunother Cancer
. 2024 Jan;
12(1).
PMID: 38272561
Background: Recent trials suggest that programmed cell death 1 (PD-1)-directed immunotherapy may be beneficial for some patients with anal squamous cell carcinoma and biomarkers predictive of response are greatly needed....