Brandon M Blobner
Overview
Explore the profile of Brandon M Blobner including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
192
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Recent Articles
1.
Wang X, Srinivasan P, El Hamdaoui M, Blobner B, Grytz R, Kashlan O
Mol Biol Evol
. 2024 Aug;
41(8).
PMID: 39101592
The epithelial Na+ channel (ENaC) emerged early in vertebrates and has played a role in Na+ and fluid homeostasis throughout vertebrate evolution. We previously showed that proteolytic activation of the...
2.
Blobner B, Kirabo A, Kashlan O, Sheng S, Arnett D, Becker L, et al.
Hypertension
. 2022 Oct;
79(11):2573-2582.
PMID: 36193739
Background: The epithelial Na channel (ENaC) is intrinsically linked to fluid volume homeostasis and blood pressure. Specific rare mutations in , , and , genes encoding the α, β, and...
3.
Fu D, Blobner B, Greer P, Lafyatis R, Bellin M, Whitcomb D
Gastroenterology
. 2022 Oct;
164(2):289-292.e4.
PMID: 36191639
No abstract available.
4.
Kelly T, Sun X, He K, Brown M, Gagliano Taliun S, Hellwege J, et al.
Hypertension
. 2022 Jun;
79(8):1656-1667.
PMID: 35652341
Background: The availability of whole-genome sequencing data in large studies has enabled the assessment of coding and noncoding variants across the allele frequency spectrum for their associations with blood pressure....
5.
Blobner B, Saloman J, Shelton Ohlsen C, Brand R, Lafyatis R, Bottino R, et al.
Am J Physiol Gastrointest Liver Physiol
. 2021 Sep;
321(5):G449-G460.
PMID: 34523348
Chronic pancreatitis (CP) is a complex inflammatory disorder with numerous associated genetic and environmental risk factors. The most distressing characteristic of CP is recalcitrant pain, often requiring surgical resection including...
6.
Blobner B, Bellin M, Beilman G, Shelton C, Park H, Whitcomb D
Pancreas
. 2020 Aug;
49(8):1037-1043.
PMID: 32769850
Objectives: To determine if RNA collected from pancreatic tissue, without the use of RNAlater, is useful for RNA sequencing (RNA-seq) despite degradation, and if so, then, via RNA-seq analysis, how...
7.
Shi S, Mutchler S, Blobner B, Kashlan O, Kleyman T
J Biol Chem
. 2018 May;
293(27):10757-10766.
PMID: 29743244
The MEC-4/MEC-10 channel mediates the worm's response to gentle body touch and is activated by laminar shear stress (LSS) when expressed in oocytes. Substitutions at multiple sites within the second...
8.
Blobner B, Wang X, Kashlan O
J Biol Chem
. 2018 Feb;
293(13):4928-4939.
PMID: 29425099
The epithelial Na channel (ENaC) is a member of the ENaC/degenerin family of ion channels. In the structure of a related family member, the "thumb" domain's base interacts with the...
9.
Kashlan O, Kinlough C, Myerburg M, Shi S, Chen J, Blobner B, et al.
Am J Physiol Renal Physiol
. 2017 Dec;
314(3):F483-F492.
PMID: 29187368
Epithelial Na channel (ENaC) subunits undergo N-linked glycosylation in the endoplasmic reticulum where they assemble into an αβγ complex. Six, 13, and 5 consensus sites (Asn-X-Ser/Thr) for N-glycosylation reside in...
10.
Kashlan O, Blobner B, Zuzek Z, Tolino M, Kleyman T
J Biol Chem
. 2014 Nov;
290(1):568-76.
PMID: 25389295
The epithelial Na(+) channel (ENaC) has a key role in the regulation of extracellular fluid volume and blood pressure. ENaC belongs to a family of ion channels that sense the...