Brandon H Hayes
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Explore the profile of Brandon H Hayes including associated specialties, affiliations and a list of published articles.
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116
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Recent Articles
1.
Highly pathogenic avian influenza management policy in domestic poultry: from reacting to preventing
Vergne T, Paul M, Guinat C, Delpont M, Hayes B, Lambert S, et al.
Euro Surveill
. 2024 Oct;
29(42).
PMID: 39421953
The emergence of clade 2.3.4.4b H5N1 highly pathogenic avian influenza (HPAI) viruses in 2021 has led to unprecedented epidemics in poultry, changing epidemiological patterns of year-round infections in resident wild...
2.
Hayes B, Wang M, Zhu H, Phan S, Dooling L, Andrechak J, et al.
Elife
. 2024 May;
12.
PMID: 38805560
Solid tumors generally exhibit chromosome copy number variation, which is typically caused by chromosomal instability (CIN) in mitosis. The resulting aneuploidy can drive evolution and associates with poor prognosis in...
3.
Tobin M, Pfeifer C, Zhu P, Hayes B, Wang M, Vashisth M, et al.
Mol Biol Cell
. 2023 Oct;
34(13):br19.
PMID: 37903225
Chromosome numbers often change dynamically in tumors and cultured cells, which complicates therapy as well as understanding genotype-mechanotype relationships. Here we use a live-cell "ChReporter" method to identify cells with...
4.
Hayes B, Vergne T, Andraud M, Rose N
Front Vet Sci
. 2023 Sep;
10:1225446.
PMID: 37745209
Modeling of infectious diseases at the livestock-wildlife interface is a unique subset of mathematical modeling with many innate challenges. To ascertain the characteristics of the models used in these scenarios,...
5.
Hayes B, Zhu H, Andrechak J, Dooling L, Discher D
PNAS Nexus
. 2023 Aug;
2(8):pgad243.
PMID: 37593202
Phagocytic elimination of solid tumors by innate immune cells seems attractive for immunotherapy, particularly because of the possibilities for acquired immunity. However, the approach remains challenging, with blockade of the...
6.
Hayes B, Zhu P, Wang M, Pfeifer C, Xia Y, Phan S, et al.
J Cell Sci
. 2023 Jun;
136(11).
PMID: 37288769
The mechanical environment of a cell can have many effects, but whether it impacts the DNA sequence of a cell has remained unexamined. To investigate this, we developed a live-cell...
7.
Wang M, Phan S, Hayes B, Discher D
Chromosoma
. 2023 May;
133(1):77-92.
PMID: 37256347
Chromosome gains or losses often lead to copy number variations (CNV) and loss of heterozygosity (LOH). Both quantities are low in hematologic "liquid" cancers versus solid tumors in data of...
8.
Dooling L, Andrechak J, Hayes B, Kadu S, Zhang W, Pan R, et al.
Nat Biomed Eng
. 2023 Apr;
7(9):1081-1096.
PMID: 37095318
In solid tumours, the abundance of macrophages is typically associated with a poor prognosis. However, macrophage clusters in tumour-cell nests have been associated with survival in some tumour types. Here,...
9.
Hayes B, Wang M, Zhu H, Phan S, Dooling L, Andrechak J, et al.
bioRxiv
. 2023 Apr;
PMID: 37066426
Chromosomal instability (CIN), a state in which cells undergo mitotic aberrations that generate chromosome copy number variations, generates aneuploidy and is thought to drive cancer evolution. Although associated with poor...
10.
Andrechak J, Dooling L, Tobin M, Zhang W, Hayes B, Lee J, et al.
Cancers (Basel)
. 2022 Apr;
14(8).
PMID: 35454837
The macrophage checkpoint interaction CD47-SIRPα is an emerging target for cancer therapy, but clinical trials of monoclonal anti-CD47 show efficacy only in liquid tumors when combined with tumor-opsonizing IgG. Here,...