Brandon C Cox
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Explore the profile of Brandon C Cox including associated specialties, affiliations and a list of published articles.
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32
Citations
922
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Recent Articles
1.
Singh J, Randle M, Walters B, Cox B
Front Cell Neurosci
. 2024 Apr;
18:1369282.
PMID: 38566840
Introduction: Hair cells (HCs) of the cochlea are responsible for sound transduction and hearing perception in mammals. Genetic mutations in the transcription factor cause non-syndromic autosomal dominant hearing loss in...
2.
Ghimire M, Cai R, Ling L, Brownell K, Wisner K, Cox B, et al.
Front Neurosci
. 2023 Jun;
17:1197909.
PMID: 37304018
Tinnitus impacts between 10-20% of the population. Individuals most troubled by their tinnitus have their attention bound to and are distracted by, their tinnitus percept. While numerous treatments to ameliorate...
3.
Ciani Berlingeri A, Pujol R, Cox B, Stone J
Hear Res
. 2022 Nov;
426:108642.
PMID: 36334348
Sox2 is a transcription factor that is necessary in the mammalian inner ear for development of sensory hair cells and supporting cells. Sox2 is expressed in supporting cells of adult...
4.
Generotti C, Cox B, Singh J, Hamilton D, McKenzie E, OMalley Jr B, et al.
Sci Rep
. 2022 Oct;
12(1):18032.
PMID: 36302835
A mouse model with cisplatin-induced ototoxicity was used in addition to human samples from the ITMAT Biobank at the University of Pennsylvania. Mouse auditory brainstem responses (ABR), inner ear histology,...
5.
Heuermann M, Matos S, Hamilton D, Cox B
Front Cell Neurosci
. 2022 Oct;
16:841864.
PMID: 36187289
After a damaging insult, hair cells can spontaneously regenerate from cochlear supporting cells within the first week of life. While the regenerated cells express several markers of immature hair cells...
6.
Stone J, Pujol R, Nguyen T, Cox B
J Neurosci
. 2021 Jun;
41(29):6217-6233.
PMID: 34099510
The sense of balance relies on vestibular hair cells, which detect head motions. Mammals have two types of vestibular hair cell, I and II, with unique morphological, molecular, and physiological...
7.
Chrysostomou E, Zhou L, Darcy Y, Graves K, Doetzlhofer A, Cox B
J Neurosci
. 2020 Oct;
40(49):9401-9413.
PMID: 33127852
During cochlear development, the Notch ligand JAGGED 1 (JAG1) plays an important role in the specification of the prosensory region, which gives rise to sound-sensing hair cells and neighboring supporting...
8.
Beebe N, Sowick C, Kristaponyte I, Galazyuk A, Vetter D, Cox B, et al.
Hear Res
. 2020 Jan;
388:107896.
PMID: 31982642
The development of knockin mice with Cre recombinase expressed under the control of the promoter for choline acetyltransferase (ChAT) has allowed experimental manipulation of cholinergic circuits. However, currently available ChAT...
9.
Hicks K, Wisner S, Cox B, Stone J
Hear Res
. 2019 Nov;
385:107838.
PMID: 31751832
In amniotes, head movements are encoded by two types of vestibular hair cells (type I and type II) with unique morphology, physiology, and innervation. After hair cell destruction in mature...
10.
Naples J, Ruckenstein M, Singh J, Cox B, Li D
Otol Neurotol
. 2019 Nov;
41(1):115-122.
PMID: 31746818
Hypothesis: Local administration of the calcium-channel blocker (CCB), diltiazem, via intratympanic (IT) chitosan-glycerophosphate (CGP) hydrogel will protect against cisplatin-induced ototoxicity. Background: Cisplatin induces calcium-mediated apoptosis of cochlear outer hair cells...