Bram Van den Bergh
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Explore the profile of Bram Van den Bergh including associated specialties, affiliations and a list of published articles.
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37
Citations
1289
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Recent Articles
11.
Clauwers C, Lood C, Van den Bergh B, van Noort V, Michiels C
Sci Rep
. 2020 Mar;
10(1):4348.
PMID: 32132564
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
12.
Windels E, Ben Meriem Z, Zahir T, Verstrepen K, Hersen P, Van den Bergh B, et al.
Commun Biol
. 2019 Dec;
2:426.
PMID: 31815194
When exposed to lethal doses of antibiotics, bacterial populations are most often not completely eradicated. A small number of phenotypic variants, defined as 'persisters', are refractory to antibiotics and survive...
13.
Windels E, Michiels J, Van den Bergh B, Fauvart M, Michiels J
mBio
. 2019 Sep;
10(5).
PMID: 31506315
Antibiotic resistance poses an alarming and ever-increasing threat to modern health care. Although the current antibiotic crisis is widely acknowledged, actions taken so far have proved insufficient to slow down...
14.
Verstraeten N, Gkekas S, Kint C, Deckers B, Van den Bergh B, Herpels P, et al.
Mol Microbiol
. 2019 Sep;
112(5):1593-1608.
PMID: 31498933
Obg is a versatile GTPase that plays a pivotal role in bacterial persistence. We previously showed that the Escherichia coli homolog ObgE exerts this activity through transcriptional activation of a...
15.
Windels E, Michiels J, Fauvart M, Wenseleers T, Van den Bergh B, Michiels J
ISME J
. 2019 Jan;
13(5):1239-1251.
PMID: 30647458
Persisters are transiently antibiotic-tolerant cells that complicate the treatment of bacterial infections. Both theory and experiments have suggested that persisters facilitate genetic resistance by constituting an evolutionary reservoir of viable...
16.
Van den Bergh B, Swings T, Fauvart M, Michiels J
Microbiol Mol Biol Rev
. 2018 Jul;
82(3).
PMID: 30045954
In experimental evolution, laboratory-controlled conditions select for the adaptation of species, which can be monitored in real time. Despite the current popularity of such experiments, nature's most pervasive biological force...
17.
Swings T, Marciano D, Atri B, Bosserman R, Wang C, Leysen M, et al.
Nat Commun
. 2018 Jun;
9(1):2231.
PMID: 29884781
CRISPR advances genome engineering by directing endonuclease sequence specificity with a guide RNA molecule (gRNA). For precisely targeting a gene for modification, each genetic construct requires a unique gRNA. By...
18.
Fauvart M, Van den Bergh B, Michiels J
Mol Cell
. 2018 Jun;
70(5):763-764.
PMID: 29883603
Antibiotic-tolerant persister cells are difficult to eradicate by conventional classes of antibiotics. Kim and colleagues have discovered a new class of synthetic retinoid antibiotics that kill Staphylococcus aureus persisters by...
19.
Clauwers C, Lood C, Van den Bergh B, van Noort V, Michiels C
Sci Rep
. 2017 Nov;
7(1):15426.
PMID: 29133849
Clostridium botulinum is an anaerobic sporeforming bacterium that is notorious for producing a potent neurotoxin. Spores of C. botulinum can survive mild food processing treatments and subsequently germinate, multiply, produce...
20.
Swings T, Van den Bergh B, Wuyts S, Oeyen E, Voordeckers K, Verstrepen K, et al.
Elife
. 2017 May;
6.
PMID: 28460660
While specific mutations allow organisms to adapt to stressful environments, most changes in an organism's DNA negatively impact fitness. The mutation rate is therefore strictly regulated and often considered a...