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Bram M P Verhagen

Explore the profile of Bram M P Verhagen including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 207
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Recent Articles
1.
Krijger P, Hoek T, Boersma S, Donders L, Broeders M, Pieterse M, et al.
Nat Biotechnol . 2021 Sep; 39(10):1182-1184. PMID: 34584248
No abstract available.
2.
Sonneveld S, Verhagen B, Tanenbaum M
Trends Cell Biol . 2020 May; 30(8):606-618. PMID: 32461030
During mRNA translation, the genetic information stored in mRNA is translated into a protein sequence. It is imperative that the genetic information is translated with high precision. Surprisingly, however, recent...
3.
Khuperkar D, Hoek T, Sonneveld S, Verhagen B, Boersma S, Tanenbaum M
Nat Protoc . 2020 Feb; 15(4):1371-1398. PMID: 32076351
mRNA translation is a key step in gene expression. Proper regulation of translation efficiency ensures correct protein expression levels in the cell, which is essential to cell function. Different methods...
4.
Boersma S, Khuperkar D, Verhagen B, Sonneveld S, Grimm J, Lavis L, et al.
Cell . 2019 Jun; 178(2):458-472.e19. PMID: 31178119
mRNA translation is a key step in decoding genetic information. Genetic decoding is surprisingly heterogeneous because multiple distinct polypeptides can be synthesized from a single mRNA sequence. To study translational...
5.
Hoek T, Khuperkar D, Lindeboom R, Sonneveld S, Verhagen B, Boersma S, et al.
Mol Cell . 2019 Jun; 75(2):324-339.e11. PMID: 31155380
Nonsense-mediated decay (NMD) is a surveillance system that degrades mRNAs containing a premature termination codon (PTC) and plays important roles in protein homeostasis and disease. The efficiency of NMD is...