Bradly P Nicholson
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Explore the profile of Bradly P Nicholson including associated specialties, affiliations and a list of published articles.
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36
Citations
662
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Recent Articles
11.
Paterson S, Kar S, Ung S, Gardener Z, Bergstrom E, Ascough S, et al.
Am J Respir Crit Care Med
. 2021 Jul;
204(7):826-841.
PMID: 34256007
Suboptimal vaccine immunogenicity and antigenic mismatch, compounded by poor uptake, means that influenza remains a major global disease. T cells recognizing peptides derived from conserved viral proteins could enhance vaccine-induced...
12.
Tsalik E, Henao R, Montgomery J, Nawrocki J, Aydin M, Lydon E, et al.
Crit Care Med
. 2021 May;
49(10):1651-1663.
PMID: 33938716
Objectives: Host gene expression signatures discriminate bacterial and viral infection but have not been translated to a clinical test platform. This study enrolled an independent cohort of patients to describe...
13.
Meredith H, Kularatna S, Nagaro K, Nagahawatte A, Bodinayake C, Kurukulasooriya R, et al.
Antimicrob Resist Infect Control
. 2021 May;
10(1):72.
PMID: 33931120
Background: The timing of and risk factors for intestinal colonization with multidrug-resistant Enterobacteriaceae (MDRE) are still poorly understood in areas with high MDRE carriage. We determined the prevalence, timing, and...
14.
McClain M, Constantine F, Henao R, Liu Y, Tsalik E, Burke T, et al.
Nat Commun
. 2021 Feb;
12(1):1079.
PMID: 33597532
SARS-CoV-2 infection has been shown to trigger a wide spectrum of immune responses and clinical manifestations in human hosts. Here, we sought to elucidate novel aspects of the host response...
15.
Giroux N, Ding S, McClain M, Burke T, Petzold E, Chung H, et al.
bioRxiv
. 2020 Dec;
PMID: 33300002
SARS-CoV-2 infection triggers highly variable host responses and causes varying degrees of illness in humans. We sought to harness the peripheral blood mononuclear cell (PBMC) response over the course of...
16.
Doshi R, Hoff N, Bratcher A, Mukadi P, Gadoth A, Nicholson B, et al.
J Infect Dis
. 2020 Dec;
226(4):608-615.
PMID: 33269402
Background: Health care workers (HCW) are more likely to be exposed to Ebola virus (EBOV) during an outbreak compared to people in the general population due to close physical contact...
17.
Vanderburg S, Wijayaratne G, Danthanarayana N, Jayamaha J, Piyasiri B, Halloluwa C, et al.
BMJ Open
. 2020 Nov;
10(11):e040612.
PMID: 33158834
Objectives: To determine aetiology of illness among children and adults presenting during outbreak of severe respiratory illness in Southern Province, Sri Lanka, in 2018. Design: Prospective, cross-sectional study. Setting: 1600-bed,...
18.
McClain M, Constantine F, Nicholson B, Nichols M, Burke T, Henao R, et al.
Lancet Infect Dis
. 2020 Sep;
21(3):396-404.
PMID: 32979932
Background: Early and accurate identification of individuals with viral infections is crucial for clinical management and public health interventions. We aimed to assess the ability of transcriptomic biomarkers to identify...
19.
McClain M, Constantine F, Henao R, Liu Y, Tsalik E, Burke T, et al.
medRxiv
. 2020 Aug;
PMID: 32743603
In order to elucidate novel aspects of the host response to SARS-CoV-2 we performed RNA sequencing on peripheral blood samples across 77 timepoints from 46 subjects with COVID-19 and compared...
20.
Tillekeratne L, Suchindran S, Ko E, Petzold E, Bodinayake C, Nagahawatte A, et al.
Open Forum Infect Dis
. 2020 Jul;
7(6):ofaa194.
PMID: 32617371
Background: Pathogen-based diagnostics for acute respiratory infection (ARI) have limited ability to detect etiology of illness. We previously showed that peripheral blood-based host gene expression classifiers accurately identify bacterial and...