Bradley M Kearney
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Explore the profile of Bradley M Kearney including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
271
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0
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Recent Articles
1.
Goto H, Ishikiriyama T, Oe K, Asaga R, Sato H, Mori K, et al.
Sci Rep
. 2025 Feb;
15(1):7197.
PMID: 40021940
Heat-related illnesses cause multiple organ injuries, including acute kidney injury (AKI). Recent studies have reported that heat-induced AKI can progress to chronic kidney disease (CKD). We previously reported that urinary...
2.
Nakashima H, Kearney B, Kinoshita M
Biomolecules
. 2025 Jan;
15(1).
PMID: 39858420
The liver is an indispensable metabolic organ, responsible for accumulating and transporting various nutritional compounds in hepatocytes. However, the transport of these materials from the liver is an energetically intensive...
3.
Shirato Y, Hsueh A, Ab Mutalib N, Deng Y, Suematsu R, Kato A, et al.
ACS Omega
. 2024 Mar;
9(9):10825-10833.
PMID: 38463262
Various miniature Clark-type oxygen electrodes (COEs), which are typically used to measure dissolved oxygen (DO) concentration in cellular respiration, have been developed since the 1980s. Arrays with individually addressable electrodes...
4.
Goto H, Nakashima H, Mori K, Tanoue K, Ito S, Kearney B, et al.
Am J Physiol Renal Physiol
. 2023 Dec;
326(3):F338-F351.
PMID: 38095023
A major complication of heat-related illness is the development of acute kidney injury (AKI) and damage to kidney tubular cells. Because kidney tubular cells use fatty acids as a major...
5.
Nakashima H, Kearney B, Kato A, Miyazaki H, Ito S, Nakashima M, et al.
Cytometry A
. 2023 Aug;
103(11):902-914.
PMID: 37606087
Liver macrophages are critical components of systemic immune system defense mechanisms. F4/80 Kupffer cells (KCs) are the predominant liver-resident macrophages and the first immune cells to contact pathogens entering the...
6.
Ishida O, Hagisawa K, Yamanaka N, Nakashima H, Kearney B, Tsutsumi K, et al.
J Thromb Haemost
. 2023 Mar;
21(7):1934-1942.
PMID: 36990156
Background: Fibrinogen γ-chain peptide-coated, adenosine 5'-diphosphate (ADP)-encapsulated liposomes (H12-ADP-liposomes) are potent hemostatic adjuvants that promote platelet thrombi formation at bleeding sites. Although we have reported the efficacy of these liposomes...
7.
Ito S, Goto H, Tanoue K, Koiwai K, Ishikiriyama T, Kearney B, et al.
J Leukoc Biol
. 2023 Feb;
113(4):400-413.
PMID: 36802006
The mortality rate for acute kidney injury (AKI) due to sepsis remains high, and effective therapies based on its pathogenesis remain elusive. Macrophages are crucial for clearing bacteria from vital...
8.
McGhee L, Yerramilli S, Nadolny R, Casal C, Kearney B, Taylor H, et al.
Med J (Ft Sam Houst Tex)
. 2021 Mar;
(PB 8-21-01/02/03):83-89.
PMID: 33666917
With limited clinical resources, burgeoning testing requests from Army and other Service units to clinical laboratories, and the continued spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) throughout the...
9.
Kearney B, Schwabe M, Marcus K, Roberts D, Dechene M, Swartz P, et al.
Proteins
. 2019 Jul;
88(1):152-165.
PMID: 31294888
Water and ligand binding play critical roles in the structure and function of proteins, yet their binding sites and significance are difficult to predict a priori. Multiple solvent crystal structures...
10.
Fetics S, Guterres H, Kearney B, Buhrman G, Ma B, Nussinov R, et al.
Structure
. 2015 Feb;
23(3):505-516.
PMID: 25684575
The Ras/Raf/MEK/ERK signal transduction pathway is a major regulator of cell proliferation activated by Ras-guanosine triphosphate (GTP). The oncogenic mutant RasQ61L is not able to hydrolyze GTP in the presence...