Bradley Hack
Overview
Explore the profile of Bradley Hack including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
166
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Recent Articles
1.
Ecanow J, Ecanow D, Hack B, Leloudas N, Prasad P
Diagnostics (Basel)
. 2023 Jul;
13(13).
PMID: 37443620
Because of the limited specificity of diagnostic imaging, many breast lesions referred for biopsy turn out to be benign. The objective of this study was to evaluate whether diffusion tensor...
2.
Prasad P, Li L, Hack B, Leloudas N, Sprague S
Kidney Int Rep
. 2023 May;
8(5):1057-1067.
PMID: 37180507
Introduction: Kidney blood oxygenation level dependent (BOLD) magnetic resonance imaging (MRI) has shown great promise in evaluating relative oxygen availability. This method is quite efficacious in evaluating acute responses to...
3.
Li L, Thacker J, Li W, Hack B, Wang C, Kohn O, et al.
Am J Nephrol
. 2021 Jan;
51(12):966-974.
PMID: 33508835
Background: The estimated glomerular filtration rate (eGFR) is frequently used to monitor progression of kidney disease. Multiple values have to be obtained, sometimes over years to determine the rate of...
4.
Li L, Hack B, Seeliger E, Prasad P
Methods Mol Biol
. 2021 Jan;
2216:171-185.
PMID: 33476000
The role of hypoxia in renal disease and injury has long been suggested but much work still remains, especially as it relates to human translation. Invasive pO probes are feasible...
5.
Li L, Milani B, Pruijm M, Kohn O, Sprague S, Hack B, et al.
MAGMA
. 2019 Dec;
33(1):113-120.
PMID: 31823276
Objective: Blood oxygenation level dependent (BOLD) MRI technique is used to evaluate changes in intra-renal oxygenation in chronic kidney disease (CKD). The purpose of this study was to evaluate if...
6.
Prasad P, Li L, Thacker J, Li W, Hack B, Kohn O, et al.
Am J Nephrol
. 2019 Jan;
49(2):114-124.
PMID: 30669143
Background: Chronic hypoxia is a well-recognized factor in the pathogenesis of chronic kidney disease (CKD). Loss of microcirculation is thought to lead to enhanced renal hypoxia, which in turn results...
7.
Foxley S, Zamora M, Hack B, Alexander R, Roman B, Quigg R, et al.
Brain Res
. 2013 Feb;
1504:85-96.
PMID: 23410788
Complement activation and inflammation are key disease features of systemic lupus erythematosus. Curcumin is an anti-inflammatory agent that inhibits the complement cascade. Therefore, we hypothesized that curcumin will be protective...
8.
Jacob A, Hack B, Chen P, Quigg R, Alexander J
J Neurochem
. 2011 Sep;
119(5):1041-51.
PMID: 21929539
Inflammation is a key factor in a number of neurodegenerative diseases including systemic lupus erythematosus. The complement system is an important mechanism in initiating and amplifying inflammation. Our recent studies...
9.
Jacob A, Hack B, Bai T, Brorson J, Quigg R, Alexander J
J Neuroimmunol
. 2010 Mar;
221(1-2):46-52.
PMID: 20207017
To investigate the role of C5a generated on complement activation in brain, the lupus model, MRL/lpr mice were treated with C5a receptor(R) antagonist (ant). Neutrophil infiltration, ICAM, TNF-alpha and iNOS...
10.
Jacob A, Hack B, Chiang E, Garcia J, Quigg R, Alexander J
FASEB J
. 2010 Jan;
24(6):1682-8.
PMID: 20065106
The blood-brain barrier (BBB) is a crucial anatomic location in the brain. Its dysfunction complicates many neurodegenerative diseases, from acute conditions, such as sepsis, to chronic diseases, such as systemic...