Boris M Hartmann
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Explore the profile of Boris M Hartmann including associated specialties, affiliations and a list of published articles.
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22
Citations
1234
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Recent Articles
1.
Nudelman I, Kudrin D, Nudelman G, Deshpande R, Hartmann B, Kleinstein S, et al.
Front Immunol
. 2021 Aug;
12:691758.
PMID: 34335598
Influenza is a serious global health threat that shows varying pathogenicity among different virus strains. Understanding similarities and differences among activated functional pathways in the host responses can help elucidate...
2.
Cappuccio A, Jensen S, Hartmann B, Sealfon S, Soumelis V, Zaslavsky E
Elife
. 2020 Nov;
9.
PMID: 33225996
From cellular activation to drug combinations, immunological responses are shaped by the action of multiple stimuli. Synergistic and antagonistic interactions between stimuli play major roles in shaping immune processes. To...
3.
Monteagudo P, Munoz-Moreno R, Fribourg M, Potla U, Mena I, Marjanovic N, et al.
J Virol
. 2019 Oct;
94(1).
PMID: 31597767
The influenza A virus (IAV) nonstructural protein 1 (NS1) contributes to disease pathogenesis through the inhibition of host innate immune responses. Dendritic cells (DCs) release interferons (IFNs) and proinflammatory cytokines...
4.
Ramos I, Smith G, Ruf-Zamojski F, Martinez-Romero C, Fribourg M, Carbajal E, et al.
J Virol
. 2019 Aug;
93(20).
PMID: 31375585
Early interactions of influenza A virus (IAV) with respiratory epithelium might determine the outcome of infection. The study of global cellular innate immune responses often masks multiple aspects of the...
5.
Mao W, Zaslavsky E, Hartmann B, Sealfon S, Chikina M
Nat Methods
. 2019 Jun;
16(7):607-610.
PMID: 31249421
A major challenge in gene expression analysis is to accurately infer relevant biological insights, such as variation in cell-type proportion or pathway activity, from global gene expression studies. We present...
6.
Lee Y, Wong A, Tadych A, Hartmann B, Park C, DeJesus V, et al.
Nat Methods
. 2018 Nov;
15(12):1049-1052.
PMID: 30478325
A key unmet challenge in interpreting omics experiments is inferring biological meaning in the context of public functional genomics data. We developed a computational framework, Your Evidence Tailored Integration (YETI;...
7.
Ruf-Zamojski F, Ge Y, Nair V, Zamojski M, Pincas H, Toufaily C, et al.
Nucleic Acids Res
. 2018 Oct;
46(21):11370-11380.
PMID: 30357357
Immediate-early response genes (IEGs) are rapidly and transiently induced following an extracellular signal. Elucidating the IEG response patterns in single cells (SCs) requires assaying large numbers of timed samples at...
8.
DAvola D, Villacorta-Martin C, Martins-Filho S, Craig A, Labgaa I, von Felden J, et al.
Sci Rep
. 2018 Aug;
8(1):11570.
PMID: 30068984
Patients with hepatocellular carcinoma (HCC) release tumor cells to the bloodstream, which can be detected using cell surface markers. Despite numerous reports suggest a direct correlation between the number of...
9.
Hartmann B, Albrecht R, Zaslavsky E, Nudelman G, Pincas H, Marjanovic N, et al.
Nat Commun
. 2017 Dec;
8(1):1931.
PMID: 29203926
The risk of emerging pandemic influenza A viruses (IAVs) that approach the devastating 1918 strain motivates finding strain-specific host-pathogen mechanisms. During infection, dendritic cells (DC) mature into antigen-presenting cells that...
10.
Cummings R, Barbet G, Bongers G, Hartmann B, Gettler K, Muniz L, et al.
Nature
. 2016 Nov;
539(7630):565-569.
PMID: 27828940
Recognition and removal of apoptotic cells by professional phagocytes, including dendritic cells and macrophages, preserves immune self-tolerance and prevents chronic inflammation and autoimmune pathologies. The diverse array of phagocytes that...