Boping Liu
Overview
Explore the profile of Boping Liu including associated specialties, affiliations and a list of published articles.
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Articles
58
Citations
1042
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Recent Articles
1.
Tian D, Tan T, Kuan Hai R, Wang G, Mohamed F, Yu Z, et al.
J Am Chem Soc
. 2024 Oct;
146(45):31321-31329.
PMID: 39475529
The optimization of hit compounds into drug candidates is a pivotal phase in drug discovery but often hampered by cumbersome manual synthesis of derivatives. While automated organic molecule synthesis has...
2.
Wu X, Liang J, Meng L, Wang B, Liu B, Jin Y
Int J Biol Macromol
. 2024 Oct;
282(Pt 1):136325.
PMID: 39414203
Molecular design of small-molecule inhibitors targeting programmed cell death-1 (PD-1)/programmed cell death ligand-1 (PD-L1) pathway has been recognized as an active research area by the clinical success of cancer immunotherapy....
3.
Guo Y, Tong J, Liang J, Shi K, Song X, Guo Z, et al.
RSC Adv
. 2024 Aug;
14(36):25908-25917.
PMID: 39157581
This study investigated the binding mechanisms of the flavonoids apigenin (Api), kaempferol (Kmp), and quercetin (Que) to the PD-L1 dimer using a combination of molecular modeling and experimental techniques. The...
4.
Wang N, Wu X, Liang J, Liu B, Wang B
Mol Divers
. 2024 Jul;
28(4):2229-2244.
PMID: 39020133
Helicobacter pylori is the main causative agent of gastric cancer, especially non-cardiac gastric cancers. This bacterium relies on urease producing much ammonia to colonize the host. Herein, the study provides...
5.
Cai M, He X, Liu B
Polymers (Basel)
. 2024 Jan;
16(2).
PMID: 38257063
With the increasing demand for high-end materials, trimodal polyethylene (PE) has become a research hotspot in recent years due to its superior performance compared with bimodal PE. By means of...
6.
Guo Y, Guo Y, Guo Z, Liu B, Xu J
Molecules
. 2023 Dec;
28(23).
PMID: 38067610
Blocking the interaction between programmed cell death-1 (PD-1) and programmed cell death-ligand 1 (PD-L1) by directly targeting the PD-L1 dimer has emerged as a hot topic in the field of...
7.
Cai M, He X, Liu Z, Liu B
Phys Chem Chem Phys
. 2023 Jun;
25(27):17912-17922.
PMID: 37376922
Trimodal polyethylene (PE) has become the focus of research in recent years due to its excellent performance. By means of molecular dynamics simulations, we aim to expound the molecular mechanism...
8.
Liu R, Liu B, Tian L, Wu X, Li X, Cai D, et al.
Sci Total Environ
. 2023 Apr;
883:163615.
PMID: 37105472
Bisphenol A (BPA) has attracted growing attention as a well-known environmental pollutant due to its high risk of male reproductive toxicity. In this study, transcriptomics profiling combined with metabolomic techniques...
9.
Wu X, Wang N, Liang J, Wang B, Jin Y, Liu B, et al.
Int J Mol Sci
. 2023 Jan;
24(2).
PMID: 36674929
Using small molecules to inhibit the PD-1/PD-L1 pathway is an important approach in cancer immunotherapy. Natural compounds such as capsaicin, zucapsaicin, 6-gingerol and curcumin have been proposed to have anticancer...
10.
Liang J, Wang B, Yang Y, Liu B, Jin Y
Int J Mol Sci
. 2023 Jan;
24(2).
PMID: 36674800
Inhibitors blocking the PD-1/PD-L1 immune checkpoint demonstrate impressive anti-tumor immunity, and small molecule inhibitors disclosed by the Bristol-Myers Squibb (BMS) company have become a hot topic. In this work, by...