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Boon Seng Soh

Explore the profile of Boon Seng Soh including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 1462
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Recent Articles
1.
Tay S, Pang J, Ng W, Ng C, Khong Z, Chong Z, et al.
Sci Rep . 2024 Dec; 14(1):31182. PMID: 39732807
Signaling interplay between the histamine 1 receptor (H1R) and transient receptor potential cation channel subfamily V member 1 (TRPV1) in mediating histaminergic itch has been well-established in mammalian models, but...
2.
Fang G, Ho B, Xu H, Gong C, Qiao Z, Liao Y, et al.
ACS Nano . 2024 Aug; PMID: 39214618
Mechanical stress within organoids is a pivotal indicator in disease modeling and pharmacokinetics, yet current tools lack the ability to rapidly and dynamically screen these mechanics. Here, we introduce biocompatible...
3.
Poh B, Liew L, Soh Y, Lai R, Lim S, Ho Y, et al.
Stem Cells . 2024 Feb; 42(5):416-429. PMID: 38381602
Cardiovascular diseases (CVDs) are the leading cause of death worldwide, accounting for 31% of all deaths globally. Myocardial ischemia-reperfusion injury (IRI), a common complication of CVDs, is a major cause...
4.
Huang J, Lee J, Rau C, Pezhouman A, Yokota T, Miwa H, et al.
Circulation . 2023 Oct; 148(16):1263-1266. PMID: 37844148
No abstract available.
5.
Ho B, Pang J, Chen Y, Loh Y, An O, Yang H, et al.
Stem Cell Res Ther . 2022 Dec; 13(1):529. PMID: 36544188
Background: Tissue organoids generated from human pluripotent stem cells are valuable tools for disease modelling and to understand developmental processes. While recent progress in human cardiac organoids revealed the ability...
6.
Karkhanis A, Venkatesan G, Kambayashi R, Leow J, Han M, Izumi-Nakaseko H, et al.
Acta Pharm Sin B . 2022 Oct; 12(10):3905-3923. PMID: 36213535
Cytochrome P4502J2 (CYP2J2) metabolizes arachidonic acid (AA) to cardioprotective epoxyeicosatrienoic acids (EETs). Dronedarone, an antiarrhythmic drug prescribed for treatment of atrial fibrillation (AF) induces cardiac adverse effects (AEs) with poorly...
7.
Adihou H, Gopalakrishnan R, Forster T, Gueret S, Gasper R, Geschwindner S, et al.
Nat Commun . 2020 Oct; 11(1):5425. PMID: 33110077
Transcription factors are key protein effectors in the regulation of gene transcription, and in many cases their activity is regulated via a complex network of protein-protein interactions (PPI). The chemical...
8.
Lim G, Hor J, Ho N, Wong C, Ng S, Soh B, et al.
Theranostics . 2019 Feb; 9(2):311-323. PMID: 30809276
Motor neuron diversification and regionalization are important hallmarks of spinal cord development and rely on fine spatiotemporal release of molecular cues. Here, we present a dedicated platform to engineer complex...
9.
Li Y, Kang X, Pang J, Soh B, Yu Y, Fan Y
Protein Cell . 2018 Nov; 10(7):470-475. PMID: 30430420
No abstract available.
10.
Ho B, Loh S, Chan W, Soh B
Int J Mol Sci . 2018 Sep; 19(9). PMID: 30213032
Genome editing has been well established as a genome engineering tool that enables researchers to establish causal linkages between genetic mutation and biological phenotypes, providing further understanding of the genetic...