Bonnie C Miller
Overview
Explore the profile of Bonnie C Miller including associated specialties, affiliations and a list of published articles.
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10
Citations
386
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Recent Articles
1.
Ge Q, Nakagawa T, Wynn R, Chook Y, Miller B, Uyeda K
J Biol Chem
. 2011 Jun;
286(32):28119-27.
PMID: 21665952
Carbohydrate response element-binding protein (ChREBP) is a glucose-responsive transcription factor that plays a critical role in the glucose-mediated induction of genes involved in hepatic glycolysis and lipogenesis. Circulating blood glucose...
2.
Getachew Y, James L, Lee W, Thiele D, Miller B
Biochem Pharmacol
. 2009 Dec;
79(9):1363-71.
PMID: 20036646
Acetaminophen (APAP) hepatotoxicity results from cytochrome P450 metabolism of APAP to the toxic metabolite, n-acetyl-benzoquinone imine (NAPQI), which reacts with cysteinyl residues to form APAP adducts and initiates cell injury....
3.
Getachew Y, Stout-Delgado H, Miller B, Thiele D
J Immunol
. 2008 Nov;
181(11):7810-7.
PMID: 19017970
It is well established that granzymes A and B play a role in CTL killing of target cells by the perforin-dependent granule exocytosis pathway. The functions of multiple additional granzymes...
4.
Stout-Delgado H, Getachew Y, Miller B, Thiele D
J Immunol
. 2007 Nov;
179(10):6561-7.
PMID: 17982045
Human proteinase inhibitor 9 (PI-9/serpinB9) and the murine ortholog, serine proteinase inhibitor 6 (SPI-6/serpinb9) are members of a family of intracellular serine proteinase inhibitors (serpins). PI-9 and SPI-6 expression in...
5.
Stout-Delgado H, Getachew Y, Rogers T, Miller B, Thiele D
Hepatology
. 2007 Aug;
46(5):1530-40.
PMID: 17685438
Unlabelled: Virally infected hepatocytes are resistant to cytotoxic lymphocyte killing by perforin-dependent and granzyme-dependent effector mechanisms. The present studies were designed to examine the role of serine protease inhibitor 6...
6.
Abougergi M, Gidner S, Spady D, Miller B, Thiele D
Hepatology
. 2004 Dec;
41(1):97-105.
PMID: 15619234
After intravenous injection of replication-deficient adenovirus, hepatocytes are transduced and express high levels of adenovirus-encoded genes. However, adenovirally encoded gene expression is ablated rapidly by CD8+ T-cell-dependent mechanisms. Thus, this...
7.
Ishii S, Iizuka K, Miller B, Uyeda K
Proc Natl Acad Sci U S A
. 2004 Oct;
101(44):15597-602.
PMID: 15496471
Carbohydrate response element (ChRE)-binding protein (ChREBP) is a recently discovered transcription factor that is activated in response to high glucose concentrations in liver independently of insulin. ChREBP was first identified...
8.
Barrie M, Stout H, Abougergi M, Miller B, Thiele D
J Immunol
. 2004 May;
172(10):6453-9.
PMID: 15128837
Expression of the granzyme B inhibitors, human proteinase inhibitor 9 (PI-9), or the murine orthologue, serine proteinase inhibitor 6 (SPI-6), confers resistance to CTL or NK killing by perforin- and...
9.
Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo
Miller B, Eckman E, Sambamurti K, Dobbs N, Chow K, Eckman C, et al.
Proc Natl Acad Sci U S A
. 2003 May;
100(10):6221-6.
PMID: 12732730
Factors that elevate amyloid-beta (Abeta) peptide levels are associated with an increased risk for Alzheimer's disease. Insulysin has been identified as one of several proteases potentially involved in Abeta degradation...
10.
Nguyen K, Miller B
J Immunol
. 2002 Apr;
168(9):4440-5.
PMID: 11970987
Previous studies have demonstrated that naive splenic mouse T cells express no or only very low levels of the delta-type opioid receptor (delta OR), but stimulation of mouse splenocytes with...