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Bojana Kravic

Explore the profile of Bojana Kravic including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 328
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Recent Articles
1.
Meyer H, Kravic B
Annu Rev Biochem . 2024 Apr; 93(1):367-387. PMID: 38594929
Lysosomes are the degradative endpoints of material delivered by endocytosis and autophagy and are therefore particularly prone to damage. Membrane permeabilization or full rupture of lysosomal or late endosomal compartments...
2.
Gahlot P, Kravic B, Rota G, Boom J, Levantovsky S, Schulze N, et al.
Mol Cell . 2024 Mar; 84(8):1556-1569.e10. PMID: 38503285
Cells respond to lysosomal membrane permeabilization by membrane repair or selective macroautophagy of damaged lysosomes, termed lysophagy, but it is not fully understood how this decision is made. Here, we...
3.
Kravic B, Bionda T, Siebert A, Gahlot P, Levantovsky S, Behrends C, et al.
Mol Cell . 2022 Jul; 82(14):2633-2649.e7. PMID: 35793674
Lysosomal membrane permeabilization (LMP) is an underlying feature of diverse conditions including neurodegeneration. Cells respond by extensive ubiquitylation of membrane-associated proteins for clearance of the organelle through lysophagy that is...
4.
Boom J, Kueck A, Kravic B, Muschenborn H, Giesing M, Pan D, et al.
Nat Struct Mol Biol . 2021 Nov; 28(12):964-971. PMID: 34824462
The AAA-ATPase VCP/p97/Cdc48 unfolds proteins by threading them through its central pore, but how substrates are recognized and inserted into the pore in diverse pathways has remained controversial. Here, we...
5.
Kravic B, Behrends C, Meyer H
Autophagy . 2019 Nov; 16(1):179-180. PMID: 31679434
Lysosomal membrane permeabilization or full rupture of lysosomes is a common and severe stress condition that is relevant for degenerative disease, infection and cancer. Cells respond with extensive ubiquitination of...
6.
Papadopoulos C, Kravic B, Meyer H
J Mol Biol . 2019 Aug; 432(1):231-239. PMID: 31449799
Lysosomal membrane permeabilization or full rupture of lysosomes is a common and severe stress condition that is relevant for degenerative disease, infection and cancer. If damage is limited, cells can...
7.
Eiber N, Rehman M, Kravic B, Rudolf R, Sandri M, Hashemolhosseini S
Cells . 2019 Aug; 8(8). PMID: 31434353
The protein kinase Csnk2/CK2 is important for cell proliferation, differentiation, and survival. Previously, we showed that CK2 binds distinctive proteins at neuromuscular junctions (NMJs) of mice and phosphorylates some of...
8.
Koerver L, Papadopoulos C, Liu B, Kravic B, Rota G, Brecht L, et al.
EMBO Rep . 2019 Aug; 20(10):e48014. PMID: 31432621
The autophagic clearance of damaged lysosomes by lysophagy involves extensive modification of the organelle with ubiquitin, but the underlying ubiquitination machinery is still poorly characterized. Here, we use an siRNA...
9.
Hulsmann J, Kravic B, Weith M, Gstaiger M, Aebersold R, Collins B, et al.
Mol Cell Proteomics . 2018 Mar; 17(7):1295-1307. PMID: 29599191
The ubiquitin-directed AAA-ATPase VCP/p97 facilitates degradation of damaged or misfolded proteins in diverse cellular stress response pathways. Resolving the complexity of its interactions with partner and substrate proteins and understanding...
10.
Kravic B, Harbauer A, Romanello V, Simeone L, Vogtle F, Kaiser T, et al.
Autophagy . 2017 Nov; 14(2):311-335. PMID: 29165030
In yeast, Tom22, the central component of the TOMM (translocase of outer mitochondrial membrane) receptor complex, is responsible for the recognition and translocation of synthesized mitochondrial precursor proteins, and its...