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Boer Deng

Explore the profile of Boer Deng including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 125
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Recent Articles
1.
Shen X, Wang J, Kong W, John C, Deng B, Chen S, et al.
Int J Biol Sci . 2025 Feb; 21(4):1545-1565. PMID: 39990670
Endometrial cancer (EC) is the most common gynecological malignancy, frequently characterized by PTEN deletion, activation of the AKT/mTOR pathway, and limited effective treatment options for recurrent and advanced patients. High-dose...
2.
Kong W, Deng B, Shen X, John C, Haag J, Sinha N, et al.
Gynecol Oncol . 2024 Oct; 191:116-123. PMID: 39388742
Objective: Interventions that combat obesity and its associated metabolic perturbations may decrease incidence and improve outcomes of endometrial cancer (EC). Potential options for weight loss include pharmacotherapeutic interventions such as...
3.
Chen S, Kong W, Shen X, Deng B, Haag J, Sinha N, et al.
J Cancer Res Clin Oncol . 2024 Aug; 150(8):402. PMID: 39198302
Purpose: Uterine serous carcinoma (USC) is a highly aggressive and frequently recurring subtype of endometrial cancer with limited treatment options for advanced or recurrent stages. Sulindac, a classic non-steroidal anti-inflammatory...
4.
Deng B, Kong W, Han C, Zhou C, Li J, Song D, et al.
Int J Med Sci . 2024 Aug; 21(10):2000-2010. PMID: 39113881
To study the effects of prior pelvic radiotherapy on bone marrow suppression in recurrent cervical cancer patients during chemotherapy. The cases of 129 patients with recurrent cervical cancer were reviewed,...
5.
Shen X, Wang J, Deng B, Zhao Z, Chen S, Kong W, et al.
Antioxidants (Basel) . 2024 May; 13(5). PMID: 38790722
Ascorbate (vitamin C) is an essential vitamin for the human body and participates in various physiological processes as an important coenzyme and antioxidant. Furthermore, the role of ascorbate in the...
6.
Zhao Z, Wang J, Kong W, Newton M, Burkett W, Sun W, et al.
Biomolecules . 2024 May; 14(5). PMID: 38786008
Epidemiological and clinical evidence have extensively documented the role of obesity in the development of endometrial cancer. However, the effect of fatty acids on cell growth in endometrial cancer has...
7.
Zhao Z, Wang J, Kong W, Fang Z, Coleman M, Milne G, et al.
Gynecol Oncol . 2024 Apr; 186:126-136. PMID: 38669767
Objective: Overweight/obesity is the strongest risk factor for endometrial cancer (EC), and weight management can reduce that risk and improve survival. We aimed to establish the differential benefits of intermittent...
8.
Shen X, Wang J, Deng B, Chen S, John C, Zhao Z, et al.
Gynecol Oncol . 2024 Mar; 183:93-102. PMID: 38555710
Objective: Uterine serous carcinoma is a highly aggressive non-endometrioid subtype of endometrial cancer with poor survival rates overall, creating a strong need for new therapeutic strategies to improve outcomes. High-dose...
9.
Deng B, Kong W, Shen X, Han C, Zhao Z, Chen S, et al.
J Transl Med . 2024 Mar; 22(1):290. PMID: 38500157
Lipid metabolism is widely reprogrammed in tumor cells. Lipid droplet is a common organelle existing in most mammal cells, and its complex and dynamic functions in maintaining redox and metabolic...
10.
Deng B, Kong W, Suo H, Shen X, Newton M, Burkett W, et al.
Cancers (Basel) . 2023 Nov; 15(22). PMID: 38001668
Reprogramming of fatty acid metabolism promotes cell growth and metastasis through a variety of processes that stimulate signaling molecules, energy storage, and membrane biosynthesis in endometrial cancer. Oleic acid is...