Bizhi Shang
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Explore the profile of Bizhi Shang including associated specialties, affiliations and a list of published articles.
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9
Citations
119
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Recent Articles
1.
Luo J, Lian Q, Zhu D, Zhao M, Mei T, Shang B, et al.
Genes Dis
. 2023 Jul;
10(4):1564-1581.
PMID: 37397520
Glaucoma is the leading cause of irreversible blindness worldwide. In the pathogenesis of glaucoma, activated microglia can lead to retinal ganglion cells (RGCs) apoptosis and death, however, the molecular mechanisms...
2.
Xu W, Liu X, Han W, Wu K, Zhao M, Mei T, et al.
Cell Commun Signal
. 2023 Jun;
21(1):134.
PMID: 37316948
Background: Age-related macular degeneration (AMD), characterized by the degeneration of retinal pigment epithelium (RPE) and photoreceptors, is the leading cause of irreversible vision impairment among the elderly. RPE senescence is...
3.
Mei T, Wu J, Wu K, Zhao M, Luo J, Liu X, et al.
Ann Transl Med
. 2023 Feb;
11(1):3.
PMID: 36760251
Background: Retinal ischemia-reperfusion (RIR) is a common pathological condition that can lead to retinal ganglion cell (RGC) death and visual impairment. However, the pathogenesis of RGC loss and visual impairment...
4.
Yang Z, Wu J, Wu K, Luo J, Li C, Zhang J, et al.
J Med Chem
. 2022 Aug;
65(17):11745-11758.
PMID: 36007247
Based on the synergistic therapeutic effect of nitric oxide (NO) and Rho-associated protein kinase (ROCK) inhibitors on glaucoma, a new group of NO-donating ripasudil derivatives - was designed, synthesized, and...
5.
Wu K, Zhou K, Zhao M, Xiang L, Mei T, Xu W, et al.
Exp Eye Res
. 2022 Jun;
221:109142.
PMID: 35691375
Diabetic retinopathy (DR) is one of the most common blindness in working-age adults. Transcription factor 7 like 2 (TCF7L2) is a susceptibility gene of DR, however, its roles in the...
6.
Zhao M, Mei T, Shang B, Zou B, Lian Q, Xu W, et al.
Front Cell Dev Biol
. 2021 Dec;
9:788422.
PMID: 34926465
Congenital cataract is one of the leading causes of blindness in children worldwide. About one-third of congenital cataracts are caused by genetic defects. LSS, which encodes lanosterol synthase, is a...
7.
Wu D, Jian C, Peng Q, Hou T, Wu K, Shang B, et al.
Cell Death Dis
. 2020 Mar;
11(3):181.
PMID: 32165613
Fatty acids are the most major substrate source for adult cardiac energy generation. Prohibitin 2 (PHB2), a highly conserved protein located in mitochondrial inner membrane, plays key roles in cellular...
8.
Lian Q, Zhao M, Li T, Wu K, Zhu D, Shang B, et al.
Exp Eye Res
. 2019 Mar;
181:271-276.
PMID: 30817926
To identify imaging characteristics of mouse persistent hyperplastic primary vitreous (PHPV) by Spectralis Optical Coherence Tomography (OCT), as well as to assess and compare the sensitivity and precision of OCT...
9.
Shan Y, Liang Z, Xing Q, Zhang T, Wang B, Tian S, et al.
Nat Commun
. 2017 Sep;
8(1):672.
PMID: 28939884
Polycomb repressive complex 2 and the epigenetic mark that it deposits, H3K27me3, are evolutionarily conserved and play critical roles in development and cancer. However, their roles in cell fate decisions...