Birke J Benedikter
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Explore the profile of Birke J Benedikter including associated specialties, affiliations and a list of published articles.
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24
Citations
516
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Recent Articles
1.
Vallbona-Garcia A, Lindsey P, Kamps R, Stassen A, Nguyen N, van Tienen F, et al.
Front Ophthalmol (Lausanne)
. 2024 Jul;
3:1309836.
PMID: 38983060
Introduction: Primary open-angle glaucoma (POAG) is a characteristic optic neuropathy, caused by degeneration of the optic nerve-forming neurons, the retinal ganglion cells (RGCs). High intraocular pressure (IOP) and aging have...
2.
You W, Knoops K, Berendschot T, Benedikter B, Webers C, Reutelingsperger C, et al.
Cell Death Discov
. 2024 Apr;
10(1):180.
PMID: 38632223
Neurodegenerative disorders are characterized by the progressive loss of structure and function of neurons, often including the death of the neuron. Previously, we reported that, by removing the cell death...
3.
Tulen C, van de Wetering C, Schiffers C, Weltjens E, Benedikter B, Leermakers P, et al.
Sci Rep
. 2024 Feb;
14(1):4821.
PMID: 38413800
Abnormal mitochondria have been observed in bronchial- and alveolar epithelial cells of patients with chronic obstructive pulmonary disease (COPD). However, it is unknown if alterations in the molecular pathways regulating...
4.
You W, Knoops K, Boesten I, Berendschot T, van Zandvoort M, Benedikter B, et al.
Cell Commun Signal
. 2024 Jan;
22(1):88.
PMID: 38297331
Background: Retinal ganglion cell (RGC) degeneration and death cause vision loss in patients with glaucoma. Regulated cell death, once initiated, is generally considered to be an irreversible process. Recently, we...
5.
Klabunde B, Wesener A, Bertrams W, Beinborn I, Paczia N, Surmann K, et al.
Nat Commun
. 2023 Oct;
14(1):5818.
PMID: 37783679
Lower respiratory tract infections caused by Streptococcus pneumoniae (Spn) are a leading cause of death globally. Here we investigate the bronchial epithelial cellular response to Spn infection on a transcriptomic,...
6.
Klabunde B, Wesener A, Bertrams W, Ringshandl S, Halder L, Vollmeister E, et al.
Cell Commun Signal
. 2023 Aug;
21(1):208.
PMID: 37592354
Background: Lung infections caused by Streptococcus pneumonia are a global leading cause of death. The reactive oxygen species HO is one of the virulence factors of Streptococcus pneumoniae. The Golgi...
7.
Vallbona-Garcia A, Hamers I, van Tienen F, Ochoteco-Asensio J, Berendschot T, De Coo I, et al.
Exp Eye Res
. 2023 May;
232:109500.
PMID: 37178956
Primary open-angle glaucoma (POAG) is characterized by optic nerve degeneration and irreversible loss of retinal ganglion cells (RGCs). The pathophysiology is not fully understood. Since RGCs have a high energy...
8.
Jung A, Schmeck B, Wiegand M, Bedenbender K, Benedikter B
Adv Drug Deliv Rev
. 2021 May;
176:113811.
PMID: 34022269
Pneumonia is among the leading causes of morbidity and mortality worldwide. Due to constant evolution of respiratory bacteria and viruses, development of drug resistance and emerging pathogens, it constitutes a...
9.
Roessler F, Benedikter B, Schmeck B, Bar N
Sci Rep
. 2021 May;
11(1):10258.
PMID: 33986404
Chronic obstructive pulmonary disease (COPD) kills over three million people worldwide every year. Despite its high global impact, the knowledge about the underlying molecular mechanisms is still limited. In this...
10.
Karwelat D, Schmeck B, Ringel M, Benedikter B, Hubner K, Beinborn I, et al.
FASEB J
. 2020 Oct;
34(12):16432-16448.
PMID: 33095949
Infections of the lung are among the leading causes of death worldwide. Despite the preactivation of innate defense programs during viral infection, secondary bacterial infection substantially elevates morbidity and mortality...