Birke J Benedikter
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Explore the profile of Birke J Benedikter including associated specialties, affiliations and a list of published articles.
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24
Citations
516
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Recent Articles
11.
Galazzo G, van Best N, Benedikter B, Janssen K, Bervoets L, Driessen C, et al.
Front Cell Infect Microbiol
. 2020 Aug;
10:403.
PMID: 32850498
Next-generation sequencing (NGS) has instigated the research on the role of the microbiome in health and disease. The compositional nature of such microbiome datasets makes it however challenging to identify...
12.
13.
Hubner K, Karwelat D, Pietsch E, Beinborn I, Winterberg S, Bedenbender K, et al.
Cell Signal
. 2019 Dec;
67:109498.
PMID: 31837465
Lower respiratory tract infections are among the most common causes of death worldwide. Main pathogens leading to these severe infections are viruses and gram-positive bacteria that activate toll-like receptor (TLR)-mediated...
14.
Stassen F, van Eijck P, Savelkoul P, Wouters E, Rohde G, Briede J, et al.
Oxid Med Cell Longev
. 2019 Sep;
2019:5204218.
PMID: 31485294
Chronic exposure to respiratory stressors increases the risk for pulmonary and cardiovascular diseases. Previously, we have shown that cigarette smoke extract (CSE) triggers the release of CD63CD81 and tissue factor...
15.
Franssen F, Alter P, Bar N, Benedikter B, Iurato S, Maier D, et al.
Int J Chron Obstruct Pulmon Dis
. 2019 Aug;
14:1465-1484.
PMID: 31371934
Chronic airflow limitation is the common denominator of patients with chronic obstructive pulmonary disease (COPD). However, it is not possible to predict morbidity and mortality of individual patients based on...
16.
Proteomic analysis reveals procoagulant properties of cigarette smoke-induced extracellular vesicles
Benedikter B, Bouwman F, Heinzmann A, Vajen T, Mariman E, Wouters E, et al.
J Extracell Vesicles
. 2019 Mar;
8(1):1585163.
PMID: 30863515
Airway epithelial cells secrete extracellular vesicles (EVs) under basal conditions and when exposed to cigarette smoke extract (CSE). Getting insights into the composition of these EVs will help unravel their...
17.
Benedikter B, Wouters E, Savelkoul P, Rohde G, Stassen F
J Toxicol Environ Health B Crit Rev
. 2018 May;
21(3):142-160.
PMID: 29714636
Extracellular vesicles (EV) are secreted signaling entities that enhance various pathological processes when released in response to cellular stresses. Respiratory exposures such as cigarette smoke and air pollution exert cellular...
18.
Benedikter B, Weseler A, Wouters E, Savelkoul P, Rohde G, Stassen F
Cell Mol Life Sci
. 2018 Mar;
75(13):2321-2337.
PMID: 29594387
Extracellular vesicles (EVs), including microvesicles and exosomes, are emerging as important regulators of homeostasis and pathophysiology. During pro-inflammatory and pro-oxidant conditions, EV release is induced. As EVs released under such...
19.
Volgers C, Benedikter B, Grauls G, Savelkoul P, Stassen F
BMC Microbiol
. 2017 Nov;
17(1):216.
PMID: 29132302
Background: During infection, inflammation is partially driven by the release of mediators which facilitate intercellular communication. Amongst these mediators are small membrane vesicles (MVs) that can be released by both...
20.
Benedikter B, Bouwman F, Vajen T, Heinzmann A, Grauls G, Mariman E, et al.
Sci Rep
. 2017 Nov;
7(1):15297.
PMID: 29127410
Appropriate isolation methods are essential for unravelling the relative contribution of extracellular vesicles (EVs) and the EV-free secretome to homeostasis and disease. We hypothesized that ultrafiltration followed by size exclusion...