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Birgit Singer-Kruger

Explore the profile of Birgit Singer-Kruger including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 151
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Recent Articles
1.
Singer-Kruger B, Jansen R
Methods Mol Biol . 2022 May; 2477:261-274. PMID: 35524122
Enzyme-catalyzed proximity labeling (PL) has proven to be a valuable resource for proteomic mapping of subcellular compartments and protein networks in living cells. We have used engineered ascorbate peroxidase (APEX2)...
2.
Singer-Kruger B, Frohlich T, Franz-Wachtel M, Nalpas N, Macek B, Jansen R
FEBS J . 2019 Jul; 287(2):325-344. PMID: 31323700
Enzyme-catalyzed proximity labeling (PL) with the engineered ascorbate peroxidase APEX2 is a novel approach to map organelle compartmentalization and protein networks in living cells. Current procedures developed for mammalian cells...
3.
Singer-Kruger B, Jansen R
RNA Biol . 2014 Dec; 11(8):1031-9. PMID: 25482891
mRNA localization and localized translation is a common mechanism that contributes to cell polarity and cellular asymmetry. In metazoan, mRNA transport participates in embryonic axis determination and neuronal plasticity. Since...
4.
Barbosa S, Pratte D, Schwarz H, Pipkorn R, Singer-Kruger B
Traffic . 2010 May; 11(8):1092-106. PMID: 20477991
Yeast Dop1p is an essential protein that is highly conserved in evolution and whose function is largely unknown. Here, we provide evidence that Dop1p localizes to endosomes and exists in...
5.
Singer-Kruger B, Lasic M, Burger A, Hausser A, Pipkorn R, Wang Y
EMBO J . 2008 Apr; 27(10):1423-35. PMID: 18418388
The Gga proteins represent a family of ubiquitously expressed clathrin adaptors engaged in vesicle budding at the tubular endosomal network/trans Golgi network. Their membrane recruitment is commonly thought to involve...
6.
Bottcher C, Wicky S, Schwarz H, Singer-Kruger B
FEBS Lett . 2006 Jan; 580(2):633-41. PMID: 16406366
Sjl2p is one of three yeast phosphoinositide 5'-phosphatases that belong to the conserved family of synaptojanins. Here, we show that Sjl2p is specifically associated with cortical actin patches which aggregate...
7.
Wicky S, Schwarz H, Singer-Kruger B
Mol Cell Biol . 2004 Aug; 24(17):7402-18. PMID: 15314152
Neo1p is an essential yeast member of the highly conserved Drs2 family of P-type ATPases with proposed aminophospholipid translocase activity. Here we present evidence that Neo1p localizes to endosomes and...
8.
Wicky S, Frischmuth S, Singer-Kruger B
FEBS Lett . 2003 Feb; 537(1-3):35-41. PMID: 12606027
In this study we identified a novel protein, Bsp1p, that interacts directly with two yeast synaptojanins, Sjl2p and Sjl3p, but not with Sjl1p. The interaction takes place via the Sac1/polyphosphoinositide...
9.
Jochum A, Jackson D, Schwarz H, Pipkorn R, Singer-Kruger B
Mol Cell Biol . 2002 Jun; 22(13):4914-28. PMID: 12052896
We previously described the isolation of ysl2-1 due to its genetic interaction with Delta ypt51/vps21, a mutant with a deletion of the coding sequence for the yeast Rab5 homolog, which...