Birgit S Koppetsch
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Explore the profile of Birgit S Koppetsch including associated specialties, affiliations and a list of published articles.
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13
Citations
1237
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Recent Articles
1.
Yu T, Blyton M, Abajorga M, Koppetsch B, Ho S, Xu B, et al.
Cell
. 2025 Mar;
PMID: 40056902
Koala retrovirus-A (KoRV-A) is spreading through wild koalas in a north-to-south wave while transducing the germ line, modifying the inherited genome as it transitions to an endogenous retrovirus. Previously, we...
2.
Yu T, Blyton M, Koppetsch B, Abajorga M, Luban J, Chappell K, et al.
Res Sq
. 2025 Jan;
PMID: 39764129
Background: Koala Retrovirus-A is a gamma-retrovirus that is spreading across wild koala populations through horizontal and vertical transmission, contributing significantly to genomic diversity across and even within koala populations. Previous...
3.
Yu T, Koppetsch B, Pagliarani S, Johnston S, Silverstein N, Luban J, et al.
Cell
. 2019 Oct;
179(3):632-643.e12.
PMID: 31607510
Antisense Piwi-interacting RNAs (piRNAs) guide silencing of established transposons during germline development, and sense piRNAs drive ping-pong amplification of the antisense pool, but how the germline responds to genome invasion...
4.
Zhang Z, Koppetsch B, Wang J, Tipping C, Weng Z, Theurkauf W, et al.
EMBO J
. 2014 Mar;
33(6):536-9.
PMID: 24652836
No abstract available.
5.
Zhang F, Wang J, Xu J, Zhang Z, Koppetsch B, Schultz N, et al.
Cell
. 2012 Nov;
151(4):871-884.
PMID: 23141543
piRNAs silence transposons during germline development. In Drosophila, transcripts from heterochromatic clusters are processed into primary piRNAs in the perinuclear nuage. The nuclear DEAD box protein UAP56 has been previously...
6.
Khurana J, Wang J, Xu J, Koppetsch B, Thomson T, Nowosielska A, et al.
Cell
. 2011 Dec;
147(7):1551-63.
PMID: 22196730
Transposons evolve rapidly and can mobilize and trigger genetic instability. Piwi-interacting RNAs (piRNAs) silence these genome pathogens, but it is unclear how the piRNA pathway adapts to invasion of new...
7.
Zhang Z, Xu J, Koppetsch B, Wang J, Tipping C, Ma S, et al.
Mol Cell
. 2011 Nov;
44(4):572-84.
PMID: 22099305
piRNAs guide PIWI proteins to silence transposons in animal germ cells. Reciprocal cycles of piRNA-directed RNA cleavage--catalyzed by the PIWI proteins Aubergine (Aub) and Argonaute3 (Ago3) in Drosophila melanogaster--expand the...
8.
Klattenhoff C, Xi H, Li C, Lee S, Xu J, Khurana J, et al.
Cell
. 2009 Sep;
138(6):1137-49.
PMID: 19732946
Piwi-interacting RNAs (piRNAs) silence transposons and maintain genome integrity during germline development. In Drosophila, transposon-rich heterochromatic clusters encode piRNAs either on both genomic strands (dual-strand clusters) or predominantly one genomic...
9.
Varmark H, Sparks C, Nordberg J, Koppetsch B, Theurkauf W
Cell Cycle
. 2009 Aug;
8(18):2951-63.
PMID: 19713770
Progression through the G(2)/M transition following DNA damage is linked to cytokinesis failure and mitotic death. In four different transformed cell lines and two human embryonic stem cell lines, we...
10.
Takada S, Kwak S, Koppetsch B, Theurkauf W
Development
. 2007 Apr;
134(9):1737-44.
PMID: 17409117
The 13 syncytial cleavage divisions that initiate Drosophila embryogenesis are under maternal genetic control. The switch to zygotic regulation of development at the midblastula transition (MBT) follows mitosis 13, when...