Bing-Yi Chen
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Explore the profile of Bing-Yi Chen including associated specialties, affiliations and a list of published articles.
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8
Citations
65
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Recent Articles
1.
Yu P, Hou D, Chang B, Liu N, Xu C, Chen X, et al.
Dev Cell
. 2024 May;
59(15):1954-1971.e7.
PMID: 38776924
A significant variation in chromatin accessibility is an epigenetic feature of leukemia. The cause of this variation in leukemia, however, remains elusive. Here, we identify SMARCA5, a core ATPase of...
2.
Jin J, Chen B, Deng C, Chen J, Xu F, Tao Y, et al.
Sci Adv
. 2023 Nov;
9(48):eadi7375.
PMID: 38019913
Myelodysplastic syndrome (MDS) is a group of clonal hematopoietic neoplasms originating from hematopoietic stem progenitor cells (HSPCs). We previously identified frequent roundabout guidance receptor 1 () mutations in patients with...
3.
Fei M, Wang Y, Chang B, Xue K, Dong F, Huang D, et al.
Blood
. 2023 Jun;
142(10):903-917.
PMID: 37319434
The bone marrow microenvironment (BMM) can regulate leukemia stem cells (LSCs) via secreted factors. Increasing evidence suggests that dissecting the mechanisms by which the BMM maintains LSCs may lead to...
4.
Li X, Wu J, Liu P, Li Z, Wang Y, Chen B, et al.
Leukemia
. 2022 Nov;
37(1):164-177.
PMID: 36352191
The patients with relapsed and refractory diffuse large B-cell lymphoma (DLBCL) have poor prognosis, and a novel and effective therapeutic strategy for these patients is urgently needed. Although ubiquitin-specific protease...
5.
Hu C, Chen B, Li Z, Yang T, Xu C, Yang R, et al.
Cell Res
. 2022 Oct;
32(12):1105-1123.
PMID: 36302855
Aberrant self-renewal of leukemia initiation cells (LICs) drives aggressive acute myeloid leukemia (AML). Here, we report that UHRF1, an epigenetic regulator that recruits DNMT1 to methylate DNA, is highly expressed...
6.
Chen B, Song J, Hu C, Chen S, Zhang Q, Xu C, et al.
Blood
. 2020 Mar;
135(25):2271-2285.
PMID: 32202636
SETD2, the histone H3 lysine 36 methyltransferase, previously identified by us, plays an important role in the pathogenesis of hematologic malignancies, but its role in myelodysplastic syndromes (MDSs) has been...
7.
Huo J, Wang X, Duan Y, Fu Q, Chen B
Huan Jing Ke Xue
. 2019 Dec;
40(11):4791-4800.
PMID: 31854544
In this study, long-term continuous monitoring of atmospheric new particle formation was conducted from 2015 to 2017 in the Shanghai suburbs using a scanning mobility particle sizer (SMPS). Combined with...
8.
Wang B, Zhai H, Chen B, Zhai S, Yang H, Chen X, et al.
Hepatobiliary Pancreat Dis Int
. 2004 May;
3(2):296-9.
PMID: 15138130
Background: The most common mechanisms of multidrug resistance (MDR) in cancer cells is the expression of an energy-dependent exfflux pump. P-glycoprotein (P-gp) encoded by MDR1 gene and multidrug associated protein...