Bikash Adhikari
Overview
Explore the profile of Bikash Adhikari including associated specialties, affiliations and a list of published articles.
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26
Citations
536
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Recent Articles
1.
Miletic N, Weckesser J, Mosler T, Rathore R, Hoffmann M, Gehrtz P, et al.
ACS Chem Biol
. 2025 Feb;
20(2):507-521.
PMID: 39932098
Proteolysis targeting chimeras (PROTACs) have gained considerable attention as a new modality in drug discovery. The development of PROTACs has been mainly focused on using CRBN (Cereblon) and VHL (Von...
2.
Haag A, Nemec V, Janovska P, Bartosikova J, Adhikari B, Muller J, et al.
J Med Chem
. 2024 Dec;
68(1):506-530.
PMID: 39729064
Members of the casein kinase 1 (CK1) family have emerged as key regulators of cellular signaling and as potential drug targets. Functional annotation of the 7 human isoforms would benefit...
3.
Adhikari B, Schneider K, Diebold M, Sotriffer C, Wolf E
Elife
. 2024 Dec;
13.
PMID: 39641357
The development of proteolysis targeting chimeras (PROTACs), which induce the degradation of target proteins by bringing them into proximity with cellular E3 ubiquitin ligases, has revolutionized drug development. While the...
4.
Sflakidou E, Adhikari B, Siokatas C, Wolf E, Sarli V
ACS Pharmacol Transl Sci
. 2024 Nov;
7(11):3488-3501.
PMID: 39539259
Monopolar spindle 1 (Mps1, also known as TTK) and Aurora kinase (AURK) A and B are critical regulators of mitosis and have been linked to the progression of various cancers....
5.
Shrestha A, Halder A, Rajak K, Jha S, Lamichhane R, Oishee A, et al.
SAGE Open Med
. 2024 Jul;
12:20503121241261204.
PMID: 39070014
Background: Sodium glucose cotransporter 2 inhibitors are recommended for the treatment of heart failure due to their cardioprotective effects, despite primarily being used as antidiabetic medications. However, the comparative profile...
6.
Vogt M, Dudvarski Stankovic N, Cruz Garcia Y, Hofstetter J, Schneider K, Kuybu F, et al.
Gut
. 2024 May;
73(9):1509-1528.
PMID: 38821858
Objective: The hallmark oncogene MYC drives the progression of most tumours, but direct inhibition of MYC by a small-molecule drug has not reached clinical testing. MYC is a transcription factor...
7.
Adhikari B, Dangal A, Pandey S, Thapa B, Joshi A, Baral B
F1000Res
. 2024 Jan;
12:1366.
PMID: 38273964
Background: Though direct greenhouse gas emissions cannot be observed in health care sectors, there can exist indirect emissions contributing to global climate change. This study addresses the concept of the...
8.
Pokhrel N, Timilsina S, Awasthi N, Adhikari A, Adhikari B, Ayer S, et al.
Heliyon
. 2024 Jan;
10(1):e23156.
PMID: 38163171
Silvicultural systems are essential for effective forest management and utilize the resources by conserving biodiversity, health, and valuable services forests offer to society. However, Nepal faces a significant knowledge gap...
9.
Olorunwa O, Adhikari B, Brazel S, Popescu S, Popescu G, Shi A, et al.
Plant Physiol Biochem
. 2022 Sep;
190:133-144.
PMID: 36115267
Waterlogging causes various metabolic, physiological, and morphological changes in crops, resulting in yield loss of most legumes in rainfed and irrigated agriculture. However, research on cowpea genotypes using physiological and...
10.
Growth and Photosynthetic Responses of Cowpea Genotypes under Waterlogging at the Reproductive Stage
Olorunwa O, Adhikari B, Brazel S, Shi A, Popescu S, Popescu G, et al.
Plants (Basel)
. 2022 Sep;
11(17).
PMID: 36079697
Waterlogging is an important environmental stress limiting the productivity of crops worldwide. Cowpea ( L.) is particularly sensitive to waterlogging stress during the reproductive stage, with a consequent decline in...