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Bianqin Guo

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Articles 17
Citations 113
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Recent Articles
1.
Gan D, Wang Y, Yang X, Huang J, Zhang L, Guo B, et al.
Lab Med . 2025 Jan; PMID: 39749461
Objective: The diagnosis and prognosis of hepatocellular carcinoma (HCC) present significant challenges in clinical practice. This study aimed to evaluate the clinical utility of tumor abnormal protein (TAP), Prothrombin induced...
2.
Liao Q, Zhang R, Ou Z, Ye Y, Zeng Q, Wang Y, et al.
Mol Ther Oncol . 2024 Apr; 32(1):200762. PMID: 38596285
Circulating tumor cells (CTCs) are the seeds of distant metastases of malignant tumors and are associated with malignancy and risk of metastasis. However, tumor cells undergo epithelial-mesenchymal transition (EMT) during...
3.
Wei Y, Zhang D, Shi H, Qian H, Chen H, Zeng Q, et al.
Genes Dis . 2024 Apr; 11(4):101041. PMID: 38560503
Pyruvate dehydrogenase kinase 1 (PDK1) phosphorylates the pyruvate dehydrogenase complex, which inhibits its activity. Inhibiting pyruvate dehydrogenase complex inhibits the tricarboxylic acid cycle and the reprogramming of tumor cell metabolism...
4.
Zhou T, Qian H, Zhang D, Fang W, Yao M, Shi H, et al.
Cancer Immunol Immunother . 2024 Mar; 73(5):76. PMID: 38554213
Background: Tumor microenvironment actually reduces antitumor effect against the immune attack by exclusion of CD8T cells. Progranulin (PGRN) is a multifunctional growth factor with significant pathological effects in multiple tumors;...
5.
Fu X, Gao K, Liu N, Guo B, He M, Lai N, et al.
Mikrochim Acta . 2024 Feb; 191(3):126. PMID: 38332145
An ultrasensitive sandwich-type electrochemical immunosensor for pro-gastrin-releasing peptide (ProGRP) detection was constructed based on PtCu nanodendrites functionalized Au/polyaniline nanospheres (Au/PANI@PtCu). The prepared Au/PANI@PtCu nanocomposites not only possessed excellent electro-catalytic activity...
6.
Guo B, Li Z, Fu G, Li H, Yang J, Zhang Z, et al.
BMC Infect Dis . 2023 Dec; 23(1):895. PMID: 38124038
Background: This work aimed to study natural humoral immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Methods: Chemiluminescent immunoassay (CLIA) was used to detect the neutralizing antibody...
7.
Zhang Y, Chen H, Yuan R, Wang Y, Zhang D, Zeng Q, et al.
Mol Carcinog . 2023 Apr; 62(7):1009-1024. PMID: 37042573
Pyruvate dehydrogenase kinase 1 (PDK1) is a widely known glycolytic enzyme, and some evidence showed that PDK1 promoted breast cancer by multiple approaches. However, very few lncRNAs have been identified...
8.
Zeng Z, Guo B, Li X, Fu X, Chen Y, Wu H, et al.
Biosens Bioelectron . 2022 Sep; 217:114724. PMID: 36166888
Accurate cancer diagnosis and effective drug therapy entail sensitive and dynamic monitoring of intracellular key enzymes, since their expression level is closely related to disease progression. Simultaneous monitoring of correlated...
9.
Zeng Q, Jin F, Qian H, Chen H, Wang Y, Zhang D, et al.
Carcinogenesis . 2021 Dec; 43(2):150-159. PMID: 34922339
Breast cancer is the most common malignancy among women worldwide. Functional studies have demonstrated that miRNA dysregulation in many cases of cancer, in which miRNAs act as either oncogenes or...
10.
Guo B, Xiong X, Hasani S, Wen Y, Li A, Martinez R, et al.
Cell Death Dis . 2021 Oct; 12(11):960. PMID: 34663797
Aberrant activation of endoplasmic reticulum (ER) stress by extrinsic and intrinsic factors contributes to tumorigenesis and resistance to chemotherapies in various cancer types. Our previous studies have shown that the...