Bhavya Voleti
Overview
Explore the profile of Bhavya Voleti including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
1326
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0
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Recent Articles
1.
Jablonski A, Warren L, Usenovic M, Zhou H, Sugam J, Parmentier-Batteur S, et al.
Sci Rep
. 2021 Feb;
11(1):3438.
PMID: 33564035
ApoEε4 is a major genetic risk factor for Alzheimer's disease (AD), a disease hallmarked by extracellular amyloid-beta (Aβ) plaques and intracellular neurofibrillary tangles (NFTs). The presence of the ApoEε4 allele...
2.
Stachel S, Ginnetti A, Johnson S, Cramer P, Wang Y, Bukhtiyarova M, et al.
Bioorg Med Chem Lett
. 2020 Aug;
30(17):127403.
PMID: 32738972
High-throughput screening methods have been used to identify two novel series of inhibitors that disrupt progranulin binding to sortilin. Exploration of structure-activity relationships (SAR) resulted in compounds with sufficient potency...
3.
Jinn S, Drolet R, Cramer P, Wong A, Toolan D, Gretzula C, et al.
Proc Natl Acad Sci U S A
. 2017 Feb;
114(9):2389-2394.
PMID: 28193887
Parkinson disease (PD) is a neurodegenerative disorder pathologically characterized by nigrostriatal dopamine neuron loss and the postmortem presence of Lewy bodies, depositions of insoluble α-synuclein, and other proteins that likely...
4.
Navarria A, Wohleb E, Voleti B, Ota K, Dutheil S, Lepack A, et al.
Neurobiol Dis
. 2015 Jun;
82:254-261.
PMID: 26102021
Clinical studies demonstrate that scopolamine, a non-selective muscarinic acetylcholine receptor (mAchR) antagonist, produces rapid therapeutic effects in depressed patients, and preclinical studies report that the actions of scopolamine require glutamate...
5.
Ota K, Liu R, Voleti B, Maldonado-Aviles J, Duric V, Iwata M, et al.
Nat Med
. 2014 Apr;
20(5):531-5.
PMID: 24728411
Major depressive disorder (MDD) affects up to 17% of the population, causing profound personal suffering and economic loss. Clinical and preclinical studies have revealed that prolonged stress and MDD are...
6.
Voleti B, Navarria A, Liu R, Banasr M, Li N, Terwilliger R, et al.
Biol Psychiatry
. 2013 Jun;
74(10):742-9.
PMID: 23751205
Background: Clinical studies report that scopolamine, an acetylcholine muscarinic receptor antagonist, produces rapid antidepressant effects in depressed patients, but the mechanisms underlying the therapeutic response have not been determined. The...
7.
Kang H, Voleti B, Hajszan T, Rajkowska G, Stockmeier C, Licznerski P, et al.
Nat Med
. 2012 Aug;
18(9):1413-7.
PMID: 22885997
Previous imaging and postmortem studies have reported a lower brain volume and a smaller size and density of neurons in the dorsolateral prefrontal cortex (dlPFC) of subjects with major depressive...
8.
Voleti B, Hammond Jr D, Thirumalai A, Agrawal A
Mol Immunol
. 2012 Jul;
52(3-4):242-8.
PMID: 22750226
C-reactive protein (CRP), a plasma protein of the innate immune system, is produced by hepatocytes. A critical regulatory region (-42 to -57) on the CRP promoter contains binding site for...
9.
Son H, Banasr M, Choi M, Chae S, Licznerski P, Lee B, et al.
Proc Natl Acad Sci U S A
. 2012 Jun;
109(28):11378-83.
PMID: 22733766
Decreased neuronal dendrite branching and plasticity of the hippocampus, a limbic structure implicated in mood disorders, is thought to contribute to the symptoms of depression. However, the mechanisms underlying this...
10.
Duman R, Voleti B
Trends Neurosci
. 2012 Jan;
35(1):47-56.
PMID: 22217452
Basic and clinical studies demonstrate that stress and depression are associated with atrophy and loss of neurons and glia, which contribute to the decreased size and function of limbic brain...