Bhaumik B Patel
Overview
Explore the profile of Bhaumik B Patel including associated specialties, affiliations and a list of published articles.
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40
Citations
1187
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Recent Articles
1.
Lucas A, Bastiach D, Dahman B, Paul A, Hirani S, Sheppard V, et al.
Cardiooncology
. 2025 Feb;
11(1):12.
PMID: 39915845
Background: Androgen deprivation therapy (ADT) is the cornerstone treatment strategy for men diagnosed with high-risk prostate cancer (PC) but may increase risk for major adverse cardiovascular events (MACE). We examined...
2.
Morrone K, Strumph K, Pisacano C, Briggs J, Zipper R, Patel B, et al.
Pediatr Blood Cancer
. 2024 Oct;
72(1):e31378.
PMID: 39420509
Background: Acute chest syndrome (ACS) is a life-threatening complication of sickle cell disease (SCD). The Prevent Acute Chest Syndrome checklist (PACScheck) was created to drive appropriate ordering of opioids, incentive...
3.
Morla S, Ravikumar O, OHara C, Boothello R, Vera A, Abdelfadiel E, et al.
J Med Chem
. 2023 Jan;
66(2):1321-1338.
PMID: 36634271
Sulfated glycosaminoglycans (GAGs), or synthetic mimetics thereof, are not favorably viewed as orally bioavailable drugs owing to their high number of anionic sulfate groups. Devising an approach for oral delivery...
4.
Boothello R, Sankaranarayanan N, Sistla J, Nagarajan B, Sharon C, Chittum J, et al.
Angew Chem Int Ed Engl
. 2022 Oct;
61(49):e202211320.
PMID: 36205924
The insulin-like growth factor-1 receptor (IGF-1R) is a receptor tyrosine kinase (RTK) that plays critical roles in cancer. Microarray, computational, thermodynamic, and cellular imaging studies reveal that activation of IGF-1R...
5.
Patel N, Baranwal S, Patel B
Methods Mol Biol
. 2021 Oct;
2303:765-777.
PMID: 34626421
Cancer stem-like cells (CSC) have been implicated in resistance to conventional chemotherapy as well as invasion and metastasis resulting in tumor relapse in majority of epithelial cancers including colorectal cancer....
6.
Pingali P, Wu Y, Boothello R, Sharon C, Li H, Sistla S, et al.
Neoplasia
. 2021 Feb;
23(3):348-359.
PMID: 33640759
High-dose acetaminophen (AAP) with delayed rescue using n-acetylcysteine (NAC), the FDA-approved antidote to AAP overdose, has demonstrated promising antitumor efficacy in early phase clinical trials. However, the mechanism of action...
7.
Carpenter V, Patel B, Autorino R, Smith S, Gewirtz D, Saleh T
Biochim Biophys Acta Rev Cancer
. 2020 Sep;
1874(2):188424.
PMID: 32956765
The development of Castration-Resistant Prostate Cancer (CRPC) remains a major challenge in the treatment of this disease. While Androgen Deprivation Therapy (ADT) can result in tumor shrinkage, a primary response...
8.
Omar A, El-Araby M, Abdelghany T, Safo M, Ahmed M, Boothello R, et al.
Bioorg Chem
. 2020 Jun;
101:103953.
PMID: 32474179
Curcumin and trans-cinnamaldehyde are acrolein-based Michael acceptor compounds that are commonly found in domestic condiments, and known to cause cancer cell death via redox mechanisms. Based on the structural features...
9.
Sistla J, Morla S, Alabbas A, Kalathur R, Sharon C, Patel B, et al.
Carbohydr Polym
. 2018 Nov;
205:385-391.
PMID: 30446119
Heparanase, an endo-β-D-glucuronidase, cleaves cell surface and extracellular matrix heparan sulfate (HS) chains and plays important roles in cellular growth and metastasis. Heparanase assays reported to-date are labor intensive, complex...
10.
Boothello R, Patel N, Sharon C, Abdelfadiel E, Morla S, Brophy D, et al.
Mol Cancer Ther
. 2018 Oct;
18(1):51-61.
PMID: 30337351
Targeting of cancer stem cells (CSC) is expected to be a paradigm-shifting approach for the treatment of cancers. Cell surface proteoglycans bearing sulfated glycosaminoglycan (GAG) chains are known to play...