Bhairavi Srinageshwar
Overview
Explore the profile of Bhairavi Srinageshwar including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
213
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Recent Articles
1.
Stadler J, Garmo L, Doyle D, Cheng C, Richardson G, Waheed Z, et al.
Front Cell Dev Biol
. 2025 Jan;
12():1467417.
PMID: 39834388
Introduction: Ischemic stroke is a devastating neurovascular condition that occurs when cerebral tissue fails to receive an adequate supply of oxygen. Despite being a leading cause of death and disability...
2.
Kuhn E, Srinageshwar B, Story D, Swanson D, Sharma A, Dunbar G, et al.
Discov Nano
. 2024 Sep;
19(1):148.
PMID: 39264474
Gene therapy is an important tool for treating fetal diseases that allows for the delivery and integration of therapeutic genes into the genome of cells carrying mutations. Nanomolecules, like PAMAM...
3.
Srinageshwar B, Thompson C, Otero P, Story D, Wedster A, MacDonald B, et al.
ACS Appl Mater Interfaces
. 2024 Jul;
16(32):41907-41915.
PMID: 39083440
Polyamidoamine (PAMAM) dendrimers are nanoparticles that have a wide scope in the field of biomedicine. Previous evidence shows that the generation 4 (G4) dendrimers with a 100% amine surface (G4-NH)...
4.
Gallo K, Srinageshwar B, Ward A, Diola C, Dunbar G, Rossignol J, et al.
Brain Sci
. 2023 Jun;
13(6).
PMID: 37371348
Glioblastomas (GBs) are the most common and malignant brain tumors in adults. A protein encoded by the gene YWHAB, 14-3-3β, is commonly found to be upregulated throughout the initiation and...
5.
Gallien J, Srinageshwar B, Gallo K, Holtgrefe G, Koneru S, Otero P, et al.
Molecules
. 2021 Oct;
26(19).
PMID: 34641594
Glioblastoma (GB) is a deadly and aggressive cancer of the CNS. Even with extensive resection and chemoradiotherapy, patient survival is still only 15 months. To maintain growth and proliferation, cancer...
6.
Gharaibeh A, Maiti P, Culver R, Heileman S, Srinageshwar B, Story D, et al.
Int J Mol Sci
. 2020 Dec;
21(24).
PMID: 33333883
Huntington's disease (HD) is a genetic neurodegenerative disorder characterized by motor, cognitive, and psychiatric symptoms, accompanied by massive neuronal degeneration in the striatum. In this study, we utilized solid lipid...
7.
Srinageshwar B, Florendo M, Clark B, Johnson K, Munro N, Peruzzaro S, et al.
Pharmaceutics
. 2020 Jul;
12(7).
PMID: 32635142
Drug delivery to the brain is highly hindered by the presence of the blood-brain barrier (BBB), which prevents the entry of many potential drugs/biomolecules into the brain. One of the...
8.
Thompson C, Otero P, Srinageshwar B, Petersen R, Dunbar G, Rossignol J
Epigenomics
. 2020 May;
12(7):647-656.
PMID: 32396465
Parkinson's disease (PD) is a neurodegenerative disease with loss of dopaminergic neurons. PD has genetic and epigenetic influences that determine specific changes in the brain. Epigenetic changes result in defective...
9.
Fana M, Gallien J, Srinageshwar B, Dunbar G, Rossignol J
Int J Nanomedicine
. 2020 May;
15:2789-2808.
PMID: 32368055
Glioblastoma (GB) is a grade IV astrocytoma that maintains a poor prognosis with respect to current treatment options. Despite major advancements in the fields of surgery and chemoradiotherapy over the...
10.
Srinageshwar B, Petersen R, Dunbar G, Rossignol J
Stem Cells Transl Med
. 2020 Jan;
9(5):559-566.
PMID: 31997581
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by a CAG repeat expansions in the huntingtin gene resulting in the synthesis of a misfolded form of the huntingtin...