Bevan Cumbes
Overview
Explore the profile of Bevan Cumbes including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
79
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0
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Recent Articles
1.
Jenkins R, Davies L, Taylor P, Akiyama H, Cumbes B, Beltrami C, et al.
Am J Pathol
. 2014 Feb;
184(4):996-1009.
PMID: 24508230
Aristolochic acid nephropathy is characterized by rapidly progressive tubulointerstitial nephritis culminating in end-stage renal failure and urothelial malignancy. Profibrotic effects of aristolochic acid are linked to growth arrest of proximal...
2.
Zissimopoulos S, Viero C, Seidel M, Cumbes B, White J, Cheung I, et al.
J Cell Sci
. 2013 Aug;
126(Pt 21):5042-51.
PMID: 23943880
The ryanodine receptor (RyR) is an ion channel composed of four identical subunits mediating calcium efflux from the endo/sarcoplasmic reticulum of excitable and non-excitable cells. We present several lines of...
3.
Phillips S, Yu Y, Rossbach A, Nomikos M, Vassilakopoulou V, Livaniou E, et al.
Biochem J
. 2011 Jun;
438(3):545-53.
PMID: 21692749
Sperm PLCζ (phospholipase Cζ) is a distinct phosphoinositide-specific PLC isoform that is proposed to be the physiological trigger of egg activation and embryo development at mammalian fertilization. Recombinant PLCζ has...
4.
Nomikos M, Elgmati K, Theodoridou M, Calver B, Cumbes B, Nounesis G, et al.
Biochem J
. 2011 Jan;
434(2):211-7.
PMID: 21204786
A male infertility-linked human PLCζ (phospholipase Cζ) mutation introduced into mouse PLCζ completely abolishes both in vitro PIP(2) (phosphatidylinositol 4,5-bisphosphate) hydrolysis activity and the ability to trigger in vivo Ca2+...