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Bettina Husen

Explore the profile of Bettina Husen including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 307
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Recent Articles
1.
Bijkerk R, Aleksinskaya M, Duijs J, Veth J, Husen B, Reiche D, et al.
Clin Sci (Lond) . 2019 Jan; 133(2):239-252. PMID: 30617188
Kidney fibrosis is the common pathophysiological mechanism in end-stage renal disease characterized by excessive accumulation of myofibroblast-derived extracellular matrix. Natriuretic peptides have been demonstrated to have cyclic guanosine monophosphate (cGMP)-dependent...
2.
Yang W, Burkhardt B, Fischer L, Beirow M, Bork N, Wonne E, et al.
EXCLI J . 2016 Mar; 14:1273-90. PMID: 27004051
Aging is characterized by a progressive decrease of cellular functions, because cells gradually lose their capacity to respond to injury. Increased oxidative stress is considered to be one of the...
3.
Hueper K, Hartung D, Gutberlet M, Gueler F, Sann H, Husen B, et al.
Am J Physiol Renal Physiol . 2013 Sep; 305(10):F1428-35. PMID: 24005471
Diabetes is associated with impaired vascular reactivity and the development of diabetic nephropathy. In a rat model of streptozotocin-induced diabetic nephropathy, the effects of systemic nitric oxide (NO) synthesis inhibition...
4.
Hueper K, Hartung D, Gutberlet M, Gueler F, Sann H, Husen B, et al.
Invest Radiol . 2012 Jun; 47(7):430-7. PMID: 22659594
Objectives: The aim of this study was to investigate whether magnetic resonance (MR) diffusion tensor imaging (DTI) allows assessment of renal pathologies in a rat model of diabetic nephropathy. Materials...
5.
Vouk K, Smuc T, Guggenberger C, Ribic-Pucelj M, Sinkovec J, Husen B, et al.
J Steroid Biochem Mol Biol . 2011 Mar; 125(3-5):231-42. PMID: 21397694
In the search for novel biomarkers of endometriosis, we selected 152 genes from the GeneLogic database based on results of genome-wide expression analysis of ovarian endometriosis, plus 20 genes related...
6.
Rizner T, Brozic P, Doucette C, Turek-Etienne T, Muller-Vieira U, Sonneveld E, et al.
Steroids . 2011 Mar; 76(6):607-15. PMID: 21376746
Dydrogesterone is widely used for menstrual disorders, endometriosis, threatened and habitual abortion and postmenopausal hormone replacement therapy. Although progestins have a promiscuous nature, dydrogesterone does not have clinically relevant androgenic,...
7.
Moller G, Husen B, Kowalik D, Hirvela L, Plewczynski D, Rychlewski L, et al.
PLoS One . 2010 Jun; 5(6):e10969. PMID: 20544026
Steroid-related cancers can be treated by inhibitors of steroid metabolism. In searching for new inhibitors of human 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD 1) for the treatment of breast cancer or...
8.
Monckedieck V, Sannecke C, Husen B, Kumbartski M, Kimmig R, Totsch M, et al.
Mol Hum Reprod . 2009 Aug; 15(10):633-43. PMID: 19671596
Progestins are successfully used in the treatment of endometriosis; however, the exact mechanisms of their action are still unsolved. We here focused on the effect of different progestins on parameters...
9.
Einspanier A, Lieder K, Husen B, Ebert K, Lier S, Einspanier R, et al.
Ann N Y Acad Sci . 2009 May; 1160:140-6. PMID: 19416176
To test the hypothesis that relaxin is an important factor supporting implantation, two approaches have been carried out using a human-relevant animal model, the marmoset monkey. First, uterine mRNA transcription...
10.
Lamminen T, Saloniemi T, Huhtinen K, Koskimies P, Messinger J, Husen B, et al.
Mol Cell Endocrinol . 2008 Nov; 301(1-2):158-62. PMID: 19026716
Hydroxysteroid (17beta) dehydrogenase 1 (HSD17B1) catalyzes the reaction between the low active 17-ketosteroids and the highly active 17beta-hydroxysteroids. In the present study, we have generated transgenic (TG) mice expressing human...