Bethany P Cummings
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Explore the profile of Bethany P Cummings including associated specialties, affiliations and a list of published articles.
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56
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1193
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Recent Articles
11.
Wise J, Cummings B
Front Microbiol
. 2023 Jan;
13:1093420.
PMID: 36699589
The gut microbiome plays a significant role in maintaining host metabolic health through the production of metabolites. Comprising one of the most abundant and diverse forms of gut metabolites, bile...
12.
Bustamante J, Dawson T, Loeffler C, Marfori Z, Marchesi J, Mullish B, et al.
Nutrients
. 2022 Dec;
14(24).
PMID: 36558359
Fecal microbiota transplantation (FMT) is a promising therapeutic modality for the treatment and prevention of metabolic disease. We previously conducted a double-blind, randomized, placebo-controlled pilot trial of FMT in obese...
13.
Holter M, Saikia M, Cummings B
Front Endocrinol (Lausanne)
. 2022 Aug;
13:934775.
PMID: 35957816
As an incretin hormone, glucagon-like peptide 1 (GLP-1) lowers blood glucose levels by enhancing glucose-stimulated insulin secretion from pancreatic beta-cells. Therapies targeting the GLP-1 receptor (GLP-1R) use the classical incretin...
14.
Holter M, Phuong D, Lee I, Saikia M, Weikert L, Fountain S, et al.
Sci Adv
. 2022 Jul;
8(29):eabn3773.
PMID: 35867787
Recent studies demonstrate that α cells contribute to glucose-stimulated insulin secretion (GSIS). Glucagon-like peptide-1 receptor (GLP-1R) agonists potently potentiate GSIS, making these drugs useful for diabetes treatment. However, the role...
15.
Noto J, Piazuelo M, Shah S, Romero-Gallo J, Hart J, Di C, et al.
J Clin Invest
. 2022 Mar;
132(10).
PMID: 35316215
Gastric carcinogenesis is mediated by complex interactions among Helicobacter pylori, host, and environmental factors. Here, we demonstrate that H. pylori augmented gastric injury in INS-GAS mice under iron-deficient conditions. Mechanistically,...
16.
Saikia M, Holter M, Donahue L, Lee I, Zheng Q, Wise J, et al.
JCI Insight
. 2021 Feb;
6(3).
PMID: 33554958
Glucagon-like peptide-1 (GLP-1) is an incretin hormone that potentiates glucose-stimulated insulin secretion. GLP-1 is classically produced by gut L cells; however, under certain circumstances α cells can express the prohormone...
17.
Allegretti J, Kassam Z, Hurtado J, Marchesi J, Mullish B, Chiang A, et al.
Hormones (Athens)
. 2021 Jan;
20(1):209-211.
PMID: 33420959
Background: Fecal microbiota transplantation (FMT) has been studied for the treatment of metabolic syndrome with varying success. However, the possibility of utilizing FMT to prevent metabolic syndrome is to date...
18.
Wang Y, Gludish D, Hayashi K, Todhunter R, Krotscheck U, Johnson P, et al.
Sci Rep
. 2020 Oct;
10(1):16725.
PMID: 33028842
Lubricin is an important boundary lubricant and chondroprotective glycoprotein in synovial fluid. Both increased and decreased synovial fluid lubricin concentrations have been reported in experimental post-traumatic osteoarthritis (PTOA) animal models...
19.
Holter M, Chirikjian M, Govani V, Cummings B
Nutrients
. 2020 Aug;
12(9).
PMID: 32859104
TGR5 is a G protein-coupled bile acid receptor that is increasingly recognized as a key regulator of glucose homeostasis. While the role of TGR5 signaling in immune cells, adipocytes and...
20.