Berta N Vazquez
Overview
Explore the profile of Berta N Vazquez including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
678
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Recent Articles
1.
Gamez-Garcia A, Espinosa-Alcantud M, Bueno-Costa A, Alari-Pahissa E, Marazuela-Duque A, Thackray J, et al.
Nat Immunol
. 2024 Oct;
25(12):2308-2319.
PMID: 39424985
B lymphopoiesis is orchestrated by lineage-specific transcription factors. In B cell progenitors, lineage commitment is mediated by Pax5, which is commonly mutated in B cell acute lymphoblastic leukemia. Despite its...
2.
Tran K, Gilbert M, Vazquez B, Ianni A, Garcia B, Vaquero A, et al.
bioRxiv
. 2024 Feb;
PMID: 38370824
Sirtuins, a class of highly conserved histone/protein deacetylases, are heavily implicated in senescence and aging. The regulation of sirtuin proteins is tightly controlled both transcriptionally and translationally and via localization...
3.
Vazquez B, Fernandez-Duran I, Hernandez Y, Tarighi S, Thackray J, Espinosa-Alcantud M, et al.
Front Cell Dev Biol
. 2024 Jan;
11:1281730.
PMID: 38234684
p53 is a hallmark tumor suppressor due in part to its role in cell cycle progression, DNA damage repair, and cellular apoptosis; its protein activity interrelates with the Sirtuin family...
4.
Gonzalez J, Bosch-Presegue L, Marazuela-Duque A, Guitart-Solanes A, Espinosa-Alcantud M, Fernandez A, et al.
Front Cell Dev Biol
. 2023 Nov;
11:1293122.
PMID: 38020886
Pericentric heterochromatin (PCH) plays an essential role in the maintenance of genome integrity and alterations in PCH have been linked to cancer and aging. HP1 α, β, and γ, are...
5.
Rasti G, Becker M, Vazquez B, Espinosa-Alcantud M, Fernandez-Duran I, Gamez-Garcia A, et al.
Nucleic Acids Res
. 2023 Jun;
51(13):6754-6769.
PMID: 37309898
The Sirtuin family of NAD+-dependent enzymes plays an important role in maintaining genome stability upon stress. Several mammalian Sirtuins have been linked directly or indirectly to the regulation of DNA...
6.
Garcia-Prieto C, Alvarez-Errico D, Musulen E, Bueno-Costa A, Vazquez B, Vaquero A, et al.
Epigenetics
. 2022 Mar;
17(12):1677-1685.
PMID: 35297293
Mouse has been extensively used as a model organism in many studies to characterize biological pathways and drug effects and to mimic human diseases. Similar DNA sequences between both species...
7.
Gamez-Garcia A, Vazquez B
Genes (Basel)
. 2021 Dec;
12(12).
PMID: 34946805
The immune system undergoes major changes with age that result in altered immune populations, persistent inflammation, and a reduced ability to mount effective immune responses against pathogens and cancer cells....
8.
Vazquez B, Quartuccio S, Schindler K
MicroPubl Biol
. 2021 Nov;
2021.
PMID: 34841221
The mammalian genome encodes three Aurora protein kinase homologs (AURKA/B/C) which regulate chromosome segregation in nearly every cell type. AURKC expression is largely limited to meiotic cells. Because of the...
9.
Vazquez B, Vaquero A, Schindler K
Mol Reprod Dev
. 2020 Nov;
87(12):1175-1187.
PMID: 33184962
Transmission of genetic material through high-quality gametes to progeny requires accurate homologous chromosome recombination and segregation during meiosis. A failure to accomplish these processes can have major consequences in reproductive...
10.
Simonet N, Thackray J, Vazquez B, Ianni A, Espinosa-Alcantud M, Morales-Sanfrutos J, et al.
Sci Adv
. 2020 Aug;
6(30):eaaz2590.
PMID: 32832656
Sirtuins are key players of metabolic stress response. Originally described as deacetylases, some sirtuins also exhibit poorly understood mono-adenosine 5'-diphosphate (ADP)-ribosyltransferase (mADPRT) activity. We report that the deacetylase SirT7 is...