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Bernhard G Herrmann

Explore the profile of Bernhard G Herrmann including associated specialties, affiliations and a list of published articles. Areas
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Articles 57
Citations 2826
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Recent Articles
1.
Swanepoel C, Wang G, Zhang L, Brandl B, Bauer H, Tsaytler P, et al.
bioRxiv . 2025 Feb; PMID: 39975218
Mendelian genetics posits equal transmission of alleles, but selfish alleles can bias the transmission of large genomic regions or entire chromosomes. One long-standing question is how transmission bias evolves to...
2.
Tsaytler P, Blaess G, Scholze-Wittler M, Meierhofer D, Wittler L, Koch F, et al.
Cell Rep . 2024 Oct; 43(10):114846. PMID: 39392751
Serum response factor (SRF) is a transcription factor essential for cell proliferation, differentiation, and migration and is required for primitive streak and mesoderm formation in the embryo. The canonical roles...
3.
Batki J, Hetzel S, Schifferl D, Bolondi A, Walther M, Wittler L, et al.
Nat Cell Biol . 2024 Jun; 26(6):868-877. PMID: 38849542
Despite a distinct developmental origin, extraembryonic cells in mice contribute to gut endoderm and converge to transcriptionally resemble their embryonic counterparts. Notably, all extraembryonic progenitors share a non-canonical epigenome, raising...
4.
Tsaytler P, Blaess G, Scholze-Wittler M, Koch F, Herrmann B
Stem Cell Reports . 2024 Apr; 19(5):618-628. PMID: 38579708
SOX2 is a transcription factor involved in the regulatory network maintaining the pluripotency of embryonic stem cells in culture as well as in early embryos. In addition, SOX2 plays a...
5.
Rogala S, Ali T, Melissari M, Wahrisch S, Schuster P, Sarre A, et al.
Nat Commun . 2023 Nov; 14(1):7024. PMID: 37919291
After myocardial infarction in the adult heart the remaining, non-infarcted tissue adapts to compensate the loss of functional tissue. This adaptation requires changes in gene expression networks, which are mostly...
6.
Schifferl D, Scholze-Wittler M, Villaronga Luque A, Pustet M, Wittler L, Veenvliet J, et al.
Development . 2023 Oct; 150(22). PMID: 37882764
The node and notochord are important signaling centers organizing the dorso-ventral patterning of cells arising from neuro-mesodermal progenitors forming the embryonic body anlage. Owing to the scarcity of notochord progenitors...
7.
Ali T, Rogala S, Krause N, Bains J, Melissari M, Wahrisch S, et al.
Nucleic Acids Res . 2023 May; 51(12):6227-6237. PMID: 37207329
Long non-coding RNAs are a very versatile class of molecules that can have important roles in regulating a cells function, including regulating other genes on the transcriptional level. One of...
8.
Tsaytler P, Liu J, Blaess G, Schifferl D, Veenvliet J, Wittler L, et al.
Development . 2023 Apr; 150(10). PMID: 37082965
Cardiac lineage specification in the mouse is controlled by TGFβ and WNT signaling. From fly to fish, BMP has been identified as an indispensable heart inducer. A detailed analysis of...
9.
Gehlen J, Giel A, Kollges R, Haas S, Zhang R, Trcka J, et al.
HGG Adv . 2022 Feb; 3(2):100093. PMID: 35199045
Esophageal atresia with or without tracheoesophageal fistula (EA/TEF) is the most common congenital malformation of the upper digestive tract. This study represents the first genome-wide association study (GWAS) to identify...
10.
Schifferl D, Scholze-Wittler M, Wittler L, Veenvliet J, Koch F, Herrmann B
Development . 2021 Nov; 148(23). PMID: 34822716
The node-streak border region comprising notochord progenitor cells (NPCs) at the posterior node and neuro-mesodermal progenitor cells (NMPs) in the adjacent epiblast is the prime organizing center for axial elongation...