Bernhard Ellinger
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Explore the profile of Bernhard Ellinger including associated specialties, affiliations and a list of published articles.
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49
Citations
959
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Recent Articles
11.
Kuzikov M, Costanzi E, Reinshagen J, Esposito F, Vangeel L, Wolf M, et al.
ACS Pharmacol Transl Sci
. 2022 Mar;
4(3):1096-1110.
PMID: 35287429
Compound repurposing is an important strategy for the identification of effective treatment options against SARS-CoV-2 infection and COVID-19 disease. In this regard, SARS-CoV-2 main protease (3CL-Pro), also termed M-Pro, is...
12.
Ali A, Ellinger B, Brandt S, Betzel C, Ruhl M, Wrenger C, et al.
Microorganisms
. 2021 Aug;
9(8).
PMID: 34442660
FW57 (DSM105789) is a prolific chitinolytic fungus isolated from wood, with a chitinase activity of 0.11 ± 0.01 U/mg. We selected this strain for genome sequencing and annotation, and compiled...
13.
Magoulas G, Afroudakis P, Georgikopoulou K, Roussaki M, Borsari C, Fotopoulou T, et al.
Molecules
. 2021 Jul;
26(14).
PMID: 34299479
A library of seventeen novel ether phospholipid analogues, containing 5-membered heterocyclic rings (1,2,3-triazolyl, isoxazolyl, 1,3,4-oxadiazolyl and 1,2,4-oxadiazolyl) in the lipid portion were designed and synthesized aiming to identify optimised miltefosine...
14.
Gunther S, Reinke P, Fernandez-Garcia Y, Lieske J, Lane T, Ginn H, et al.
Science
. 2021 Apr;
372(6542):642-646.
PMID: 33811162
The coronavirus disease (COVID-19) caused by SARS-CoV-2 is creating tremendous human suffering. To date, no effective drug is available to directly treat the disease. In a search for a drug...
15.
Brandt S, Brognaro H, Ali A, Ellinger B, Maibach K, Ruhl M, et al.
Biotechnol Biofuels
. 2021 Mar;
14(1):74.
PMID: 33743779
Background: The transition to a biobased economy involving the depolymerization and fermentation of renewable agro-industrial sources is a challenge that can only be met by achieving the efficient hydrolysis of...
16.
Ellinger B, Bojkova D, Zaliani A, Cinatl J, Claussen C, Westhaus S, et al.
Sci Data
. 2021 Feb;
8(1):70.
PMID: 33637768
SARS-CoV-2 is a novel coronavirus responsible for the COVID-19 pandemic, in which acute respiratory infections are associated with high socio-economic burden. We applied high-content screening to a well-defined collection of...
17.
Brandt S, Ellinger B, van Nguyen T, Harder S, Schluter H, Hahnke R, et al.
Front Microbiol
. 2020 Oct;
11:2154.
PMID: 33071998
A prerequisite for the transition toward a biobased economy is the identification and development of efficient enzymes for the usage of renewable resources as raw material. Therefore, different xylanolytic enzymes...
18.
Robinson W, Taylor A, Lauga-Cami S, Weaver G, Arroo R, Kaiser M, et al.
Eur J Med Chem
. 2020 Oct;
209:112871.
PMID: 33070078
Human African trypanosomiasis, or sleeping sickness, is a neglected tropical disease caused by Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense which seriously affects human health in Africa. Current therapies present...
19.
Ellinger B, Pohlmann D, Woens J, Jakel F, Reinshagen J, Stocking C, et al.
Viruses
. 2020 May;
12(5).
PMID: 32466195
HIV-1 infection is a complex, multi-step process involving not only viral, but also multiple cellular factors. To date, drug discovery methods have primarily focused on the inhibition of single viral...
20.
Linciano P, Cullia G, Borsari C, Santucci M, Ferrari S, Witt G, et al.
Eur J Med Chem
. 2020 Jan;
189:112047.
PMID: 31982652
The LIBRA compound library is a collection of 522 non-commercial molecules contributed by various Italian academic laboratories. These compounds have been designed and synthesized during different medicinal chemistry programs and...