Bernardo Oldak
Overview
Explore the profile of Bernardo Oldak including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
356
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Recent Articles
1.
Oldak B, Wildschutz E, Bondarenko V, Comar M, Zhao C, Aguilera-Castrejon A, et al.
Nature
. 2023 Sep;
622(7983):562-573.
PMID: 37673118
The ability to study human post-implantation development remains limited owing to ethical and technical challenges associated with intrauterine development after implantation. Embryo-like models with spatially organized morphogenesis and structure of...
2.
Viukov S, Shani T, Bayerl J, Aguilera-Castrejon A, Oldak B, Sheban D, et al.
Stem Cell Reports
. 2022 Oct;
17(11):2484-2500.
PMID: 36270280
The recent derivation of human trophoblast stem cells (TSCs) from placental cytotrophoblasts and blastocysts opened opportunities for studying the development and function of the human placenta. Recent reports have suggested...
3.
Oldak B, Aguilera-Castrejon A, Hanna J
Curr Opin Genet Dev
. 2022 Sep;
77:101988.
PMID: 36179582
Research on early postimplantation mammalian development has been limited by the small size and intrauterine confinement of the developing embryos. Owing to the inability to observe and manipulate living embryos...
4.
Tarazi S, Aguilera-Castrejon A, Joubran C, Ghanem N, Ashouokhi S, Roncato F, et al.
Cell
. 2022 Aug;
185(18):3290-3306.e25.
PMID: 35988542
In vitro cultured stem cells with distinct developmental capacities can contribute to embryonic or extraembryonic tissues after microinjection into pre-implantation mammalian embryos. However, whether cultured stem cells can independently give...
5.
Sheban D, Shani T, Maor R, Aguilera-Castrejon A, Mor N, Oldak B, et al.
Mol Cell
. 2021 Dec;
82(1):106-122.e9.
PMID: 34875212
The fidelity of the early embryonic program is underlined by tight regulation of the chromatin. Yet, how the chromatin is organized to prohibit the reversal of the developmental program remains...
6.
Bayerl J, Ayyash M, Shani T, Manor Y, Gafni O, Massarwa R, et al.
Cell Stem Cell
. 2021 Apr;
28(9):1549-1565.e12.
PMID: 33915080
Isolating human MEK/ERK signaling-independent pluripotent stem cells (PSCs) with naive pluripotency characteristics while maintaining differentiation competence and (epi)genetic integrity remains challenging. Here, we engineer reporter systems that allow the screening...
7.
Aguilera-Castrejon A, Oldak B, Shani T, Ghanem N, Itzkovich C, Slomovich S, et al.
Nature
. 2021 Mar;
593(7857):119-124.
PMID: 33731940
The mammalian body plan is established shortly after the embryo implants into the maternal uterus, and our understanding of post-implantation developmental processes remains limited. Although pre- and peri-implantation mouse embryos...
8.
Schcolnik-Cabrera A, Juarez M, Oldak B, Cruz-Rivera M, Flisser A, Duenas-Gonzalez A, et al.
Arch Med Res
. 2020 Feb;
51(1):65-75.
PMID: 32097797
Background And Aims: Calreticulin is a chaperone and master regulator of intracellular calcium homeostasis. Several additional functions have been discovered. Human and parasite calreticulin have been shown to suppress mammary...
9.
Schcolnik-Cabrera A, Oldak B, Juarez M, Cruz-Rivera M, Flisser A, Mendlovic F
Apoptosis
. 2019 Apr;
24(3-4):245-255.
PMID: 30929105
Calreticulin (CRT) is a pleiotropic and highly conserved molecule that is mainly localized in the endoplasmic reticulum. Recently, CRT has gained special interest for its functions outside the endoplasmic reticulum...
10.
Oldak D, Garcia G, Gonzalez E, Aillon E, Falcon J, Ayala E, et al.
Int J Pediatr
. 2019 Feb;
2019:3812152.
PMID: 30713561
Background: Newborn hyperbilirubinemia is considered a worldwide health problem that demands medical evaluation. Noninvasive transcutaneous bilirubin (TcB) has been used as a screening method with different devices but there has...