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Bernadett Martinecz

Explore the profile of Bernadett Martinecz including associated specialties, affiliations and a list of published articles. Areas
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Citations 811
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Recent Articles
1.
Judak L, Chiovini B, Juhasz G, Palfi D, Mezriczky Z, Szadai Z, et al.
Nat Commun . 2022 Nov; 13(1):6715. PMID: 36344570
Neuronal plasticity has been shown to be causally linked to coincidence detection through dendritic spikes (dSpikes). We demonstrate the existence of SPW-R-associated, branch-specific, local dSpikes and their computational role in...
2.
Varga D, Menyhart A, Posfai B, Csaszar E, Lenart N, Cserep C, et al.
J Cereb Blood Flow Metab . 2020 Jan; 40(1_suppl):S67-S80. PMID: 31987008
Selective elimination of microglia from the brain was shown to dysregulate neuronal Ca signaling and to reduce the incidence of spreading depolarization (SD) during cerebral ischemia. However, the mechanisms through...
3.
Cserep C, Posfai B, Lenart N, Fekete R, Laszlo Z, Lele Z, et al.
Science . 2019 Dec; 367(6477):528-537. PMID: 31831638
Microglia are the main immune cells in the brain and have roles in brain homeostasis and neurological diseases. Mechanisms underlying microglia-neuron communication remain elusive. Here, we identified an interaction site...
4.
Wong R, Lenart N, Hill L, Toms L, Coutts G, Martinecz B, et al.
Brain Behav Immun . 2018 Nov; 76:126-138. PMID: 30453020
The cytokine interleukin-1 (IL-1) is a key contributor to neuroinflammation and brain injury, yet mechanisms by which IL-1 triggers neuronal injury remain unknown. Here we induced conditional deletion of IL-1R1...
5.
Fekete R, Cserep C, Lenart N, Toth K, Orsolits B, Martinecz B, et al.
Acta Neuropathol . 2018 Jul; 136(3):461-482. PMID: 30027450
Neurotropic herpesviruses can establish lifelong infection in humans and contribute to severe diseases including encephalitis and neurodegeneration. However, the mechanisms through which the brain's immune system recognizes and controls viral...
6.
Szollosi D, Hegedus N, Veres D, Futo I, Horvath I, Kovacs N, et al.
Mol Imaging Biol . 2018 May; 20(6):952-962. PMID: 29736562
Purpose: The purpose of this study was to evaluate a set of widely used nuclear medicine imaging agents as possible methods to study the early effects of systemic inflammation on...
7.
Szalay G, Martinecz B, Lenart N, Kornyei Z, Orsolits B, Judak L, et al.
Nat Commun . 2016 May; 7:11499. PMID: 27139776
Microglia are the main immune cells of the brain and contribute to common brain diseases. However, it is unclear how microglia influence neuronal activity and survival in the injured brain...
8.
Szigeti K, Horvath I, Veres D, Martinecz B, Lenart N, Kovacs N, et al.
J Cereb Blood Flow Metab . 2015 Jul; 35(12):1921-9. PMID: 26219594
Inflammation that develops in the brain and peripheral organs after stroke contributes profoundly to poor outcome of patients. However, mechanisms through which inflammation impacts on brain injury and overall outcome...
9.
Denes A, Pradillo J, Drake C, Sharp A, Warn P, Murray K, et al.
Ann Neurol . 2014 Mar; 75(5):670-83. PMID: 24644058
Objective: Bacterial infection contributes to diverse noninfectious diseases and worsens outcome after stroke. Streptococcus pneumoniae, the most common infection in patients at risk of stroke, is a major cause of...