Benoit Laffont
Overview
Explore the profile of Benoit Laffont including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
693
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0
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Recent Articles
1.
Kabore J, Laffont B, Diop M, Tardif M, Turgeon A, Dumaresq J, et al.
Clin Infect Dis
. 2023 May;
77(6):805-815.
PMID: 37149726
Background: Nirmatrelvir/ritonavir has shown to reduce COVID-19 hospitalization and death before Omicron, but updated real-world evidence studies are needed. This study aimed to assess whether nirmatrelvir/ritonavir reduces the risk of...
2.
Lambert M, Guellal S, Ho J, Benmoussa A, Laffont B, Belanger R, et al.
Noncoding RNA
. 2022 Jun;
8(3).
PMID: 35645341
Small RNA sequencing (sRNA-Seq) approaches unveiled sequences derived from longer non-coding RNAs, such as transfer RNA (tRNA) and ribosomal RNA (rRNA) fragments, known as tRFs and rRFs, respectively. However, rRNAs...
3.
Diallo I, Ho J, Laffont B, Laugier J, Benmoussa A, Lambert M, et al.
Int J Mol Sci
. 2021 Apr;
22(7).
PMID: 33917562
Ebola virus (EBOV) is a virulent pathogen, notorious for inducing life-threatening hemorrhagic fever, that has been responsible for several outbreaks in Africa and remains a public health threat. Yet, its...
4.
Stokes A, Pion J, Binazon O, Laffont B, Bigras M, Dubois G, et al.
Regul Toxicol Pharmacol
. 2020 Apr;
113:104648.
PMID: 32240713
The novel self-amplifying mRNA (SAM) technology for vaccines consists of an engineered replication-deficient alphavirus genome encoding an RNA-dependent RNA polymerase and the gene of the target antigen. To validate the...
5.
Laffont B, Rayner K
Can J Cardiol
. 2017 Feb;
33(3):313-324.
PMID: 28232017
MicroRNAs are short noncoding RNAs, expressed in humans and involved in sequence-specific post-transcriptional regulation of gene expression. They have emerged as key players in a wide array of biological processes,...
6.
Benmoussa A, Lee C, Laffont B, Savard P, Laugier J, Boilard E, et al.
J Nutr
. 2016 Oct;
146(11):2206-2215.
PMID: 27708120
Background: MicroRNAs are small, gene-regulatory noncoding RNA species present in large amounts in milk, where they seem to be protected against degradative conditions, presumably because of their association with exosomes....
7.
Laffont B, Corduan A, Rousseau M, Duchez A, Lee C, Boilard E, et al.
Thromb Haemost
. 2015 Sep;
115(2):311-23.
PMID: 26333874
Platelet microparticles (MPs) represent the most abundant MPs subtype in the circulation, and can mediate intercellular communication through delivery of bioactives molecules, such as cytokines, proteins, lipids and RNAs. Here,...
8.
Hubert A, Subra C, Jenabian M, Tremblay Labrecque P, Tremblay C, Laffont B, et al.
J Acquir Immune Defic Syndr
. 2015 Jul;
70(3):219-27.
PMID: 26181817
Background: Because of factors only partly understood, the generalized elevated immune activation and inflammation characterizing HIV-1-infected patients are corrected incompletely with antiretroviral therapy (ART). Extracellular vesicles (EVs) including exosomes and...
9.
Duchez A, Boudreau L, Naika G, Bollinger J, Belleannee C, Cloutier N, et al.
Proc Natl Acad Sci U S A
. 2015 Jun;
112(27):E3564-73.
PMID: 26106157
Platelets are anucleated blood elements highly potent at generating extracellular vesicles (EVs) called microparticles (MPs). Whereas EVs are accepted as an important means of intercellular communication, the mechanisms underlying platelet...
10.
Corduan A, Ple H, Laffont B, Wallon T, Plante I, Landry P, et al.
Thromb Haemost
. 2015 Feb;
113(5):1046-59.
PMID: 25673011
Platelets play an important role in haemostasis, as well as in thrombosis and coagulation processes. They harbour a wide variety of messenger RNAs (mRNAs), that can template de novo protein...