Benjamin Youngblood
Overview
Explore the profile of Benjamin Youngblood including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
889
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0
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Recent Articles
1.
Kang T, Youngblood B
Cold Spring Harb Perspect Med
. 2024 Aug;
PMID: 39134386
Type 1 diabetes (T1D) serves as an exemplar of chronic autoimmune disease characterized by insulin deficiency due to pancreatic β-cell destruction, leading to hyperglycemia and progressive organ failure. Until recently,...
2.
Soerens A, Kunzli M, Quarnstrom C, Scott M, Swanson L, Locquiao J, et al.
Nature
. 2023 Jan;
614(7949):762-766.
PMID: 36653453
Differentiated somatic mammalian cells putatively exhibit species-specific division limits that impede cancer but may constrain lifespans. To provide immunity, transiently stimulated CD8 T cells undergo unusually rapid bursts of numerous...
3.
Talleur A, Qudeimat A, Metais J, Langfitt D, Mamcarz E, Crawford J, et al.
Blood Adv
. 2022 Apr;
6(21):5737-5749.
PMID: 35446934
T cells expressing CD19-specific chimeric antigen receptors (CD19-CARs) have potent antileukemia activity in pediatric and adult patients with relapsed and/or refractory B-cell acute lymphoblastic leukemia (B-ALL). However, not all patients...
4.
Verma V, Jafarzadeh N, Boi S, Kundu S, Jiang Z, Fan Y, et al.
Nat Immunol
. 2020 Nov;
22(1):53-66.
PMID: 33230330
Regenerative stem cell-like memory (T) CD8 T cells persist longer and produce stronger effector functions. We found that MEK1/2 inhibition (MEKi) induces T that have naive phenotype with self-renewability, enhanced...
5.
Fonseca R, Beura L, Quarnstrom C, Ghoneim H, Fan Y, Zebley C, et al.
Nat Immunol
. 2020 Feb;
21(4):412-421.
PMID: 32066954
Central memory T (T) cells patrol lymph nodes and perform conventional memory responses on restimulation: proliferation, migration and differentiation into diverse T cell subsets while also self-renewing. Resident memory T...
6.
Alfei F, Kanev K, Hofmann M, Wu M, Ghoneim H, Roelli P, et al.
Nature
. 2019 Jun;
571(7764):265-269.
PMID: 31207605
Cytotoxic T cells are essential mediators of protective immunity to viral infection and malignant tumours and are a key target of immunotherapy approaches. However, prolonged exposure to cognate antigens often...
7.
Mamcarz E, Zhou S, Lockey T, Abdelsamed H, Cross S, Guolian Kang , et al.
N Engl J Med
. 2019 Apr;
380(16):1525-1534.
PMID: 30995372
Background: Allogeneic hematopoietic stem-cell transplantation for X-linked severe combined immunodeficiency (SCID-X1) often fails to reconstitute immunity associated with T cells, B cells, and natural killer (NK) cells when matched sibling...
8.
Arthur C, Patel S, Smith N, Bennett A, Kamili N, Mener A, et al.
J Immunol
. 2017 Mar;
198(7):2671-2680.
PMID: 28250159
Although RBC transfusion can result in the development of anti-RBC alloantibodies that increase the probability of life-threatening hemolytic transfusion reactions, not all patients generate anti-RBC alloantibodies. However, the factors that...