Benjamin Posorske
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Explore the profile of Benjamin Posorske including associated specialties, affiliations and a list of published articles.
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5
Citations
23
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Recent Articles
1.
Jasani N, Xu X, Posorske B, Kim Y, Wang K, Vera O, et al.
Cancer Res
. 2024 Nov;
85(2):314-328.
PMID: 39495254
Overexpression of phosphoglycerate dehydrogenase (PHGDH), the rate-limiting enzyme in the serine synthesis pathway, promotes melanomagenesis, melanoma cell proliferation, and survival of metastases in serine-low environments such as the brain. Here,...
2.
Vera O, Martinez M, Soto-Vargas Z, Wang K, Xu X, Ruiz-Buceta S, et al.
bioRxiv
. 2024 Sep;
PMID: 39282450
Transcription factor deregulation potently drives melanoma progression by dynamically and reversibly controlling gene expression programs. We previously identified the small MAF family transcription factor MAFG as a putative driver of...
3.
Jasani N, Xu X, Posorske B, Kim Y, Vera O, Tsai K, et al.
bioRxiv
. 2024 Apr;
PMID: 38659816
Overexpression of PHGDH, the rate-limiting enzyme in the serine synthesis pathway, promotes melanomagenesis, melanoma cell proliferation, and survival of metastases in serine-low environments such as the brain. While amplification explains...
4.
French S, Vijey P, Karhohs K, Wilkie A, Horin L, Ray A, et al.
J Thromb Haemost
. 2020 Jul;
18(10):2701-2711.
PMID: 32662223
Background: The mechanisms that regulate platelet biogenesis remain unclear; factors that trigger megakaryocytes (MKs) to initiate platelet production are poorly understood. Platelet formation begins with proplatelets, which are cellular extensions...
5.
Vijey P, Posorske B, Machlus K
Platelets
. 2018 Jul;
29(6):583-588.
PMID: 30047825
Megakaryocytes (MKs) are specialized precursor cells committed to producing and proliferating platelets. In a cytoskeletal-driven process, mature MKs generate platelets by releasing thin cytoplasmic extensions, named proplatelets, into the sinusoids....