Benjamin Polacco
Overview
Explore the profile of Benjamin Polacco including associated specialties, affiliations and a list of published articles.
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5
Citations
6
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Recent Articles
1.
Nourreddine S, Doctor Y, Dailamy A, Forget A, Lee Y, Chinn B, et al.
bioRxiv
. 2024 Nov;
PMID: 39574586
Towards comprehensively investigating the genotype-phenotype relationships governing the human pluripotent stem cell state, we generated an expressed genome-scale CRISPRi Perturbation Cell Atlas in KOLF2.1J human induced pluripotent stem cells (hiPSCs)...
2.
Kaushal P, Ummadi M, Jang G, Delgado Y, Makanani S, Alba K, et al.
STAR Protoc
. 2024 Nov;
5(4):103286.
PMID: 39488835
Proteins congregate into complexes to perform diverse cellular functions. Protein complexes are remodeled by protein-coding mutations or cellular signaling changes, driving phenotypic outcomes in health and disease. We present an...
3.
Janes J, Muller M, Selvaraj S, Manoel D, Stephenson J, Goncalves C, et al.
bioRxiv
. 2024 Jun;
PMID: 38854010
Genome sequencing efforts have led to the discovery of tens of millions of protein missense variants found in the human population with the majority of these having no annotated role...
4.
Kaushal P, Ummadi M, Jang G, Delgado Y, Makanani S, Blanc S, et al.
ArXiv
. 2024 May;
PMID: 38800652
Proteins congregate into complexes to perform fundamental cellular functions. Phenotypic outcomes, in health and disease, are often mechanistically driven by the remodeling of protein complexes by protein-coding mutations or cellular...
5.
OLeary P, Chen H, Doruk Y, Williamson T, Polacco B, McNeal A, et al.
Cancer Res
. 2022 Oct;
82(21):3950-3961.
PMID: 36273492
Significance: Loss of NMD proteins promotes resistance to ATR inhibitors in gastric cancer cells, which may provide a combination of therapeutic targets and biomarkers to improve the clinical utility of...