Benjamin P Lamarre
Overview
Explore the profile of Benjamin P Lamarre including associated specialties, affiliations and a list of published articles.
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2
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3
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Recent Articles
1.
Ravindranathan R, Somuncu O, da Costa A, Mukkavalli S, Lamarre B, Nguyen H, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(47):e2413954121.
PMID: 39546575
Poly (ADP-ribose) glycohydrolase (PARG) is a dePARylating enzyme which promotes DNA repair by removal of poly (ADP-ribose) (PAR) from PARylated proteins. Loss or inhibition of PARG results in replication stress...
2.
da Costa A, Somuncu O, Ravindranathan R, Mukkavalli S, Martignetti D, Nguyen H, et al.
Cancer Res
. 2024 Jun;
84(20):3435-3446.
PMID: 38885312
Recent studies suggest that PARP and POLQ inhibitors confer synthetic lethality in BRCA1-deficient tumors by accumulation of single-stranded DNA (ssDNA) gaps at replication forks. Loss of USP1, a deubiquitinating enzyme,...