Benjamin Mizukawa
Overview
Explore the profile of Benjamin Mizukawa including associated specialties, affiliations and a list of published articles.
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25
Citations
555
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Recent Articles
1.
He X, Hawkins C, Lawley L, Phan T, Park I, Joven N, et al.
Biochim Biophys Acta Mol Basis Dis
. 2024 Nov;
1871(1):167565.
PMID: 39522891
Accumulating evidence demonstrates that the "Warburg effect" that glycolysis is enhanced even in the presence of oxygen existed in hematopoietic malignancies, contributing to extracellular acidosis. G-protein coupled receptor 68 (GPR68),...
2.
Chang Y, Yamamoto K, Fujino T, Wang T, Sugimoto E, Zhang W, et al.
Cell Rep
. 2024 Aug;
43(8):114536.
PMID: 39096901
Monocytic acute myeloid leukemia (AML) responds poorly to current treatments, including venetoclax-based therapy. We conducted in vivo and in vitro CRISPR-Cas9 library screenings using a mouse monocytic AML model and...
3.
LeBlanc F, Breese E, Burns K, Chang E, Jones L, Lee L, et al.
Br J Haematol
. 2024 Jul;
205(3):1055-1066.
PMID: 39082439
Venetoclax (VEN) combined with hypomethylating agents (HMA) decitabine or azacitidine is used for adult acute myeloid leukaemia (AML), but its application in paediatric, adolescent and young adult (AYA) AML lacks...
4.
Bender J, Rubinstein J, Mizukawa B, Perentesis J, Pommert L
Pediatr Blood Cancer
. 2023 Jan;
70(4):e30214.
PMID: 36694431
Multiagent immunochemotherapy affords excellent outcomes in pediatric non-Hodgkin lymphoma (NHL); however, scarce data exist for patients unfit for intensive treatment. Rituximab, gemcitabine, and oxaliplatin (R-GemOx) is well tolerated and efficacious...
5.
Liu X, Sato N, Yabushita T, Li J, Jia Y, Tamura M, et al.
EMBO Mol Med
. 2022 Dec;
15(1):e15631.
PMID: 36453131
Inosine monophosphate dehydrogenase (IMPDH) is a rate-limiting enzyme in de novo guanine nucleotide synthesis pathway. Although IMPDH inhibitors are widely used as effective immunosuppressants, their antitumor effects have not been...
6.
Sabnis H, Shulman D, Mizukawa B, Bouvier N, Zehir A, Fangusaro J, et al.
J Clin Oncol
. 2021 Sep;
39(34):3822-3828.
PMID: 34591650
Purpose: The US Food and Drug Administration-expanded access program (EAP) uses a single patient use (SPU) mechanism to provide patient access to investigational agents in situations where no satisfactory or...
7.
Rubinstein J, Shah R, Breese E, Burns K, Mangino J, Norris R, et al.
Pediatr Blood Cancer
. 2021 May;
68(8):e29126.
PMID: 34019326
No guidelines exist for which intensive chemotherapy regimen is best in pediatric or young adult patients with high-risk posttransplant lymphoproliferative disorder (PTLD). We retrospectively reviewed patients with PTLD who received...
8.
Wunderlich M, Manning N, Sexton C, OBrien E, Byerly L, Stillwell C, et al.
Front Oncol
. 2021 Apr;
11:642466.
PMID: 33928030
Immune therapies such as blinatumomab, CD19-directed bispecific CD3 T-cell Engager (BiTE), have resulted in significant improvements in outcomes for relapsed B-cell acute lymphoblastic leukemia (B-ALL). However, up to half of...
9.
He X, Dou A, Feng S, Roman-Rivera A, Hawkins C, Lawley L, et al.
Exp Hematol
. 2020 May;
86:21-27.e2.
PMID: 32437909
Our previous study revealed that expression of G protein-coupled receptor 68 (GPR68) was upregulated in MDSL cells, a cell line representing myelodysplastic syndromes (MDS), in response to lenalidomide (LEN), and...
10.
Sabulski A, Bartlett A, Koch B, Vatner R, Mizukawa B, Phillips C
J Pediatr Hematol Oncol
. 2020 Mar;
43(4):e494-e497.
PMID: 32205781
Risk stratification and appropriate treatment selection for children with precursor B-acute lymphoblastic leukemia (B-ALL) have improved outcomes. We report the case of a 4-year-old male with a lymphomatous cavernous sinus...