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Benjamin Maneglier

Explore the profile of Benjamin Maneglier including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 456
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Recent Articles
1.
Bruzzoni-Giovanelli H, Zouali H, Sahbatou M, Maneglier B, Cayuela J, Rebollo A, et al.
Pharmaceutics . 2024 Jun; 16(6). PMID: 38931954
The tyrosine kinase Inhibitor (TKI) imatinib is approved for the treatment of the chronic phase of chronic myeloid leukemia (CP-CML). Pharmacokinetic studies have highlighted the importance of inter-patient variability on...
2.
Farfour E, Rouabah L, Bargain P, Lecuru M, Picard C, Tcherakian C, et al.
Ann Biol Clin (Paris) . 2023 Oct; 81(4):403-409. PMID: 37864446
Objectives: SARS-CoV-2 has impacted the detection of seasonal respiratory viruses. We retrospectively assessed the trend in the detection of 10 viruses in the COVID-19 area in 2 hospitals located in...
3.
Johnson-Ansah H, Maneglier B, Huguet F, Legros L, Escoffre-Barbe M, Gardembas M, et al.
Pharmaceutics . 2022 Aug; 14(8). PMID: 36015302
The registered dose for imatinib is 400 mg/d, despite high inter-patient variability in imatinib plasmatic exposure. Therapeutic drug monitoring (TDM) is routinely used to maximize a drug’s efficacy or tolerance....
4.
Osman J, Lambert J, Temple M, Devaux F, Favre R, Flaujac C, et al.
Br J Haematol . 2020 Jun; 190(5):718-722. PMID: 32542672
Complementary tools are warranted to increase the sensitivity of the initial testing for COVID-19. We identified a specific 'sandglass' aspect on the white blood cell scattergram of COVID-19 patients reflecting...
5.
Guignabert C, Phan C, Seferian A, Huertas A, Tu L, Thuillet R, et al.
J Clin Invest . 2016 Aug; 126(9):3207-18. PMID: 27482885
Pulmonary arterial hypertension (PAH) is a life-threatening disease that can be induced by dasatinib, a dual Src and BCR-ABL tyrosine kinase inhibitor that is used to treat chronic myelogenous leukemia...
6.
Prost S, Relouzat F, Spentchian M, Ouzegdouh Y, Saliba J, Massonnet G, et al.
Nature . 2015 Sep; 525(7569):380-3. PMID: 26331539
Whether cancer is maintained by a small number of stem cells or is composed of proliferating cells with approximate phenotypic equivalency is a central question in cancer biology. In the...
7.
Roth O, Spreux-Varoquaux O, Bouchet S, Rousselot P, Castaigne S, Rigaudeau S, et al.
Clin Chim Acta . 2009 Oct; 411(3-4):140-6. PMID: 19853594
Background: Imatinib, a competitive inhibitor of BCR-ABL tyrosine kinase, is now the first-line treatment for chronic myelogenous leukemia (CML). Therapeutic drug monitoring targeting trough plasma levels of about 1000ng/mL may...
8.
Maneglier B, Malleret B, Guillemin G, Spreux-Varoquaux O, Devillier P, Rogez-Kreuz C, et al.
Fundam Clin Pharmacol . 2009 Aug; 23(5):573-81. PMID: 19656212
Human immunodeficiency virus (HIV) infection is often complicated by the development of acquired immunodeficiency syndrome (AIDS) dementia complex (ADC). Implications of kynurenine pathway (KP) are suggested in ADC and other...
9.
Malleret B, Maneglier B, Karlsson I, Lebon P, Nascimbeni M, Perie L, et al.
Blood . 2008 Sep; 112(12):4598-608. PMID: 18787223
Plasmacytoid dendritic cells (pDCs) are antigen-presenting cells that develop into type-I interferon (IFN-I)-producing cells in response to pathogens. Their role in human immunodeficiency virus (HIV) pathogenesis needs to be understood....
10.
Malleret B, Karlsson I, Maneglier B, Brochard P, Delache B, Andrieu T, et al.
Immunology . 2008 Jan; 124(2):223-33. PMID: 18217951
Dendritic cells (DCs) are known to be essential for the induction and regulation of immune responses. Non-human primates are essential in biomedical research and contribute to our understanding of the...