Benjamin Lyons
Overview
Explore the profile of Benjamin Lyons including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
19
Citations
807
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Recent Articles
11.
de Crecy-Lagard V, Brochier-Armanet C, Urbonavicius J, Fernandez B, Phillips G, Lyons B, et al.
Mol Biol Evol
. 2010 Apr;
27(9):2062-77.
PMID: 20382657
Wyosine (imG) and its derivatives such as wybutosine (yW) are found at position 37 of phenylalanine-specific transfer RNA (tRNA(Phe)), 3' adjacent to the anticodon in Eucarya and Archaea. In Saccharomyces...
12.
Crecy E, Jaronski S, Lyons B, Lyons T, Keyhani N
BMC Biotechnol
. 2009 Aug;
9:74.
PMID: 19709419
Background: Filamentous fungi are the most widely used eukaryotic biocatalysts in industrial and chemical applications. Consequently, there is tremendous interest in methodology that can use the power of genetics to...
13.
El Yacoubi B, Lyons B, Cruz Y, Reddy R, Nordin B, Agnelli F, et al.
Nucleic Acids Res
. 2009 Mar;
37(9):2894-909.
PMID: 19287007
Threonylcarbamoyladenosine (t(6)A) is a universal modification found at position 37 of ANN decoding tRNAs, which imparts a unique structure to the anticodon loop enhancing its binding to ribosomes in vitro....
14.
Phillips G, El Yacoubi B, Lyons B, Alvarez S, Iwata-Reuyl D, de Crecy-Lagard V
J Bacteriol
. 2008 Oct;
190(24):7876-84.
PMID: 18931107
Queuosine (Q) and archaeosine (G(+)) are hypermodified ribonucleosides found in tRNA. Q is present in the anticodon region of tRNA(GUN) in Eukarya and Bacteria, while G(+) is found at position...
15.
Herbst R, Davies A, Natale R, Dang T, Schiller J, Garland L, et al.
Clin Cancer Res
. 2007 Oct;
13(20):6175-81.
PMID: 17947484
Purpose: Pertuzumab, a first-in-class human epidermal receptor 2 (HER2) dimerization inhibitor, is a humanized monoclonal anti-HER2 antibody that binds HER2's dimerization domain and inhibits HER2 signaling. Based on supporting preclinical...
16.
Agus D, Sweeney C, Morris M, Mendelson D, McNeel D, Ahmann F, et al.
J Clin Oncol
. 2007 Feb;
25(6):675-81.
PMID: 17308272
Purpose: Pertuzumab represents a new class of targeted anticancer agents, human epidermal growth factor receptor (HER) dimerization inhibitors. The aim of this single-arm phase II clinical study was to assess...
17.
Gordon M, Matei D, Aghajanian C, Matulonis U, Brewer M, Fleming G, et al.
J Clin Oncol
. 2006 Aug;
24(26):4324-32.
PMID: 16896006
Purpose: Ovarian cancers (OCs) frequently have HER2 activation in the absence of HER2 overexpression. Pertuzumab, a humanized antibody that prevents HER2 dimerization and inhibits multiple HER-mediated pathways, was studied in...
18.
Khanna S, Vieta E, Lyons B, Grossman F, Eerdekens M, Kramer M
Br J Psychiatry
. 2005 Sep;
187:229-34.
PMID: 16135859
Background: Severe mania is life-threatening, carries an increased risk of suicide and has a serious impact on patients and their families. Efficient and rapid control of episodes of acute mania...
19.
De Deyn P, Katz I, Brodaty H, Lyons B, Greenspan A, Burns A
Clin Neurol Neurosurg
. 2005 Jun;
107(6):497-508.
PMID: 15922506
This analysis used pooled data from three randomized, placebo-controlled trials that examined the efficacy and safety of risperidone for the treatment of agitation, aggression, and psychosis associated with dementia in...